Eur Heart J:房颤患者慢性阻塞性肺疾病的患病率、治疗和影响

2021-08-02 MedSci原创 MedSci原创

COPD在AF患者中很常见,13%的AF患者伴有COPD,并且与合并症负担增加、差异化管理和更差的结局相关,全因死亡风险增加两倍以上,此外大出血和心血管死亡风险增加。

房颤(AF)患者慢性阻塞性肺疾病(COPD)的患病率尚未明确,并且其与不良结局之间的关联经常被忽视。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员旨在评估COPD的患病率、其对AF患者临床管理和结局的影响,以及β受体阻滞剂(BBs)对COPD患者结局的影响。

研究人员根据国际准则进行了系统评价和荟萃分析,纳入了所有报告AF患者COPD患病率的研究。根据COPD和BB使用状态比较了合并症、BBs和口服抗凝剂处方以及结局(全因死亡、心血管(CV)死亡、缺血性卒中、大出血)的数据。

在46项研究中,COPD的合并患病率为13%[95%置信区间(CI)为10-16%,95%预测区间为2-47%]。COPD与较高的合并症患病率、较高的CHA2DS2-VASc评分和较低的BB处方相关[比值比(OR)为0.77,95%CI为0.61–0.98]。COPD与全因死亡(OR为2.22,95%CI为1.93-2.55)、心血管死亡(OR为1.84,95%CI为1.39-2.43)和大出血(OR为1.45,95%CI为1.17-1.80)风险相关。

COPD在AF患者中很常见,13%的AF患者伴有COPD,并且与合并症负担增加、差异化管理和更差的结局相关,全因死亡风险增加两倍以上,此外大出血和心血管死亡风险增加。BBs治疗不会增加伴有COPD的AF患者不良结局的风险。

原始出处:

Giulio Francesco Romiti.et al.Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients.European Heart Journal.2021.https://doi.org/10.1093/eurheartj/ehab453

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    2022-01-12 tomyang96
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    2021-08-14 tanxingdoctor

    学习了,谢谢啦

    0

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1696982, encodeId=3403169698249, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Jan 12 18:51:35 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1007838, encodeId=5440100e8382f, content=学习了,谢谢啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sat Aug 14 13:25:07 CST 2021, time=2021-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250746, encodeId=84cc1250e4651, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Wed Aug 04 03:51:35 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357754, encodeId=d98a135e754b4, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 04 03:51:35 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563498, encodeId=684a1563498a7, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Aug 04 03:51:35 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614609, encodeId=79db1614609c8, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Wed Aug 04 03:51:35 CST 2021, time=2021-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1004730, encodeId=aeca1004e3077, content=<a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>患者<a href='/topic/show?id=344353e0291' target=_blank style='color:#2F92EE;'>#慢性阻塞性肺疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤), TopicDto(id=53702, encryptionId=344353e0291, topicName=慢性阻塞性肺疾病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Mon Aug 02 19:48:59 CST 2021, time=2021-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031446, encodeId=420c103144657, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Mon Aug 02 15:51:35 CST 2021, time=2021-08-02, status=1, ipAttribution=)]
    2021-08-04 zhaojie88
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    2021-08-04 slcumt
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    2021-08-02 心介

    房颤,临床上碰到很多哦

    0

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