Nature:科学家发现空气中PM2.5浓度与新生儿死亡率密切相关

2018-07-02 李雯 中国生物技术网

在全球范围内,空气污染都被认为是增加人口死亡率的重要危险因素,但是关于大气颗粒物如何影响人口死亡率的来自发展中国家的证据非常有限。近期,由美国斯坦福大学Marshall Burke教授领导的团队报道了一项覆盖了非洲30个发展中国家的关于空气质量与新生儿死亡率关系的研究。目前该研究结果以Letter的形式于2018年6月27日发表在世界顶级学术期刊《Nature》上。

在全球范围内,空气污染都被认为是增加人口死亡率的重要危险因素,但是关于大气颗粒物如何影响人口死亡率的来自发展中国家的证据非常有限。近期,由美国斯坦福大学Marshall Burke教授领导的团队报道了一项覆盖了非洲30个发展中国家的关于空气质量与新生儿死亡率关系的研究。目前该研究结果以Letter的形式于2018年6月27日发表在世界顶级学术期刊《Nature》上。

该研究团队运用基于家庭问卷调查的方法,收集了2001年至2015年这15年之间来撒哈拉沙漠以南的非洲地区(sub-Saharan African)30个国家中约100万新生儿出生时间和地点的信息,并结合卫星评估的各地区空气动力学直径小于2.5μm可吸入颗粒物(PM2.5)暴露情况,以研究空气质量对非洲地区新生儿出生1年内死亡率的影响。

该团队应用固定后果回归分析(fixed-effects regression analyses)的方法,发现在撒哈拉沙漠以南的非洲地区,新生儿死亡率与空气PM2.5暴露情况呈强线性增长关系。空气中PM2.5的浓度每增加10 μg m-3可导致新生儿死亡率增加9%(95%置信区间:4-14%),且该影响在近15年来未随时间减弱也未随着家庭条件改善而减弱。

尽管过去大家普遍认为家庭条件改善可避免糟糕的环境暴露对健康带来的负面影响,但是在该研究中,并未发现富裕地区PM2.5所引起的新生儿死亡率与贫穷地区存在差异,且其他社会经济学因素或人口学特征也不可减轻PM2.5对新生儿死亡率带来的影响。

还研究还发现,调查地区内22%的新生儿死亡(95%置信区间:9-35%)可归因于空气中过高浓度的PM2.5,即PM2.5 > 2 μg m-3,且在2015年一年之内过高浓度的PM2.5导致了449000例额外新生儿死亡病例(95%置信区间:194000-709000例),该数字是既往非洲地区报道的空气质量对新生儿死亡率影响值的3倍。

最后,该研究还提示,非洲地区空气中PM2.5浓度轻微的下降就可带来强于任何已知的健康干预所带来的健康效益。

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    2018-08-13 liye789132251
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    2018-09-29 wmw990556

    不错的文章

    0

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    2018-07-04 122a54f7m32(暂无昵称)

    好文章.受教了

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    2018-07-03 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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