PNAS:PM2.5影响同期哮喘药物使用

2018-11-30 海北 MedSci原创

哮喘是医疗支出最高的慢性病之一,其每年在美国的直接医疗支出中占到超过500亿美元。与此同时,有证据表明,细颗粒物质污染会加剧哮喘症状,并产生大量经济成本。

哮喘是医疗支出最高的慢性病之一,其每年在美国的直接医疗支出中占到超过500亿美元。与此同时,有证据表明,细颗粒物质污染会加剧哮喘症状,并产生大量经济成本。
最近,为了衡量这些成本,研究人员使用一个独特的全国性面板数据集,来跟踪在2012年至2017年间哮喘患者使用救援药物的情况,以及他们暴露于PM2.5(空气动力学直径<2.5μm)的颗粒物浓度,以估计在污染和吸入药物使用之间的因果关系。
研究人员的样本由使用哮喘数字健康平台的个人组成,该平台依靠无线传感器来跟踪吸入药物使用事件的地点和时间,以及常规的非事件位置和时间指示器。这些数据可准确测量吸入药物的使用情况,并允许在空间和时间上严格分配污染暴露。
使用高频研究设计和个体固定效应,研究人员发现,每周暴露于PM2.5的量每增加1μg/ m3(12%),吸入药物使用量增加0.82%。研究人员还表明,在这种反应中存在季节性,区域性和基于收入的异质性。
使用研究中的反应预测,以及文献中关于避免哮喘症状的支付意愿的估计,研究人员表明,全国1微克/立方米的颗粒物浓度降低每年将产生近3.5亿美元的经济效益。

原始出处:

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    2019-05-10 drwjr
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    2018-12-27 huangdf
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    2019-07-31 zywlvao
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    2018-11-30 龙胆草

    学习谢谢分享

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