Cell Metabolism:要想抗衰老,先得吃得好:在抗衰老和代谢健康方面,饮食胜过“神药”

2021-11-23 “生物世界”公众号 “生物世界”公众号

三分药,七分养,这个“养”大多数时候指的正是食疗。然而,随着社会的进步,人们的生活节奏越来越快,点外卖吃快餐的现象也十分普遍,膳食平衡在这种情况下似乎更加难以保证。

常言道,三分药,七分养,这个“养”大多数时候指的正是食疗。然而,随着社会的进步,人们的生活节奏越来越快,点外卖吃快餐的现象也十分普遍,膳食平衡在这种情况下似乎更加难以保证。

相比生病后再密切注意膳食,日常的起居饮食更为重要。实际上,许多慢性代谢性疾病,如肥胖、心血管疾病等很大程度上是由于不良饮食习惯导致的。由此可见,摄入食物数量、种类以及搭配对人的身体健康起到至关重要的作用。

近日,悉尼大学的研究人员在 Cell 子刊 Cell Metabolism 上发表了题为:Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin 的研究论文。

该研究表明,在控制糖尿病、中风和心脏病等疾病方面,合理的饮食结构可能比药物更加有效。

研究人员发现,在小鼠身上,营养(包括总热量和常量营养平衡)对衰老和代谢健康的影响大于三种常用的抗衰老药物——二甲双胍、雷帕霉素、白藜芦醇

长寿和健康,是人类永恒的愿景。遗憾的是,人们一直在努力寻找能够改善新陈代谢健康和衰老的药物,却忽略了饮食习惯的重要性。许多营养物质也可以像药物一样针对特定的生化途径,从而影响人的代谢健康。

本研究的通讯作者 Charles Perkins 教授表示:“饮食是一剂良药。然而,目前的临床治疗很少考虑到药物与饮食结构的相互作用。即使这些药物的作用方式和营养信号传导途径与饮食相同。”

因此,在这项发表于 Cell Metabolism 的研究中,研究团队着手研究药物或饮食在重塑营养感应和其他代谢途径方面是否更有效,以及药物和饮食之间的相互作用是否使它们更有效。

研究模式图

研究团队设计了一项复杂的小鼠研究,涉及40种不同的饮食治疗方案,每种方案都有不同水平的蛋白质、脂肪和碳水化合物平衡,卡路里和药物含量。随后,研究人员检测了在不同饮食方案下的三种抗衰老药物(二甲双胍、雷帕霉素、白藜芦醇)对肝脏的影响。

这项研究的一个关键优势是使用了一种先进的营养几何框架。这个框架使研究小组能够考虑不同营养成分的混合和相互作用如何影响健康和疾病,而不是单独关注任何一种营养成分,这是其他营养研究的局限。

营养和表型的结果

研究团队发现,饮食中的热量摄入量和大量营养素(蛋白质、脂肪和碳水化合物)的平衡对肝脏有很大影响。其中,蛋白质和总热量摄入不仅对代谢途径有特别强大的影响,而且对控制我们细胞功能的基本过程也有特别强大的影响。

饮食结构影响肝脏蛋白质组

例如,摄入蛋白质的量会影响线粒体的活动,线粒体是细胞中产生能量的部分。这就产生了一种下游效应——它不仅影响代谢途径,还影响线粒体功能和RNA剪接等基本过程。这些基本过程均与衰老相关。

相比之下,药物的作用主要是抑制细胞对饮食的代谢反应,而不是从根本上改变它们。此外,研究人员还发现,在药物的生化效果和饮食组成之间,存在一些更具体的相互作用:白藜芦醇,对由脂肪和碳水化合物引起的细胞变化有更大的影响;二甲双胍和雷帕霉素,则阻止了饮食蛋白质对线粒体的影响。

二甲双胍、雷帕霉素和白藜芦醇对肝脏蛋白质组的影响

该研究的第一作者 David Le Couteur 表示,尽管这项研究非常复杂,但它表明同时研究多种不同的饮食是多么重要,而不是仅仅比较几种不同的饮食。这种方法是我们了解饮食、健康和生理之间相互作用的唯一途径。

总而言之,我们都知道吃的食物类型会影响我们的健康,但这项研究表明,食物还可以显着影响我们细胞中的许多过程。这让我们了解到饮食是如何影响健康和衰老的。这也提示我们,药补不如食补,改善饮食结构才是获得长寿健康的不二之选。

原始出处:

David G. Le Couteur, et al. Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin. Cell Metabolism, 2021.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (9)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
    2022-01-11 一闲
  2. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
    2022-01-14 维他命
  3. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
    2022-09-25 guojianrong
  6. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
    2021-11-24 闆锋旦
  9. [GetPortalCommentsPageByObjectIdResponse(id=1896946, encodeId=bfba1896946ea, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Jan 11 10:28:37 CST 2022, time=2022-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962635, encodeId=ba2c19626355d, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Fri Jan 14 17:28:37 CST 2022, time=2022-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1221984, encodeId=5b231221984db, content=<a href='/topic/show?id=d06e55e807f' target=_blank style='color:#2F92EE;'>#抗衰老#</a><a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a><a href='/topic/show?id=91eb2540054' target=_blank style='color:#2F92EE;'>#代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55780, encryptionId=d06e55e807f, topicName=抗衰老), TopicDto(id=90321, encryptionId=4c239032154, topicName=衰老), TopicDto(id=25400, encryptionId=91eb2540054, topicName=代谢)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:11:04 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1872316, encodeId=54f418e231632, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 01 04:28:37 CST 2021, time=2021-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888386, encodeId=68d818883866a, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Sep 25 08:28:37 CST 2022, time=2022-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571411, encodeId=2e1e15e14117b, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577278, encodeId=cece15e727814, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598147, encodeId=7700159814e80, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Nov 24 09:28:37 CST 2021, time=2021-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1073210, encodeId=064f10e321089, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=93424732566, createdName=454646258, createdTime=Tue Nov 23 15:15:05 CST 2021, time=2021-11-23, status=1, ipAttribution=)]
    2021-11-23 454646258

    0

相关资讯

肺动脉高压代谢,一个新的角度

肺动脉高压(PAH)的特征是肺血流动力学和血管生长调节受损。新陈代谢和生物能量学的改变越来越被认为是PAH的普遍特征,因为在患者的肺和心脏、该疾病的动物模型以及患者的肺来源的细胞中都发现了代谢异常。

JNER:电动假肢对截肢患者的代谢和活动的影响:一项随机交叉试验

经胫骨截肢(TTA)患者的行走不对称性更大,消耗更多的代谢能量,并且比未截肢的患者更喜欢走得慢。这些因素可能导致患者的体力活动水平下降。特别是,与未截肢的人相比,TTA的患者每天的步数较低,每次行走的

JCEM:袖状胃切除术后早期免疫细胞计数、代谢和功能的变化

在LSG手术后前三个月,就会诱导免疫细胞的组成和代谢发生显著变化。需要进一步评估减肥手术对免疫代谢的影响以及对宿主防御和代谢疾病的影响。

槟榔真的一无是处?肠道菌群表示要“取其精华”

PLOS ONE:嚼槟榔对海南人肠道菌群的影响——“薛定谔”的有益?

Nature子刊:康复后仍免疫缺陷,新冠病毒对B细胞到底还做了什么?!

SARS-CoV-2感染通过增强B细胞代谢,下调B细胞CD19表达,导致康复患者免疫缺陷。

Aging Cell:膳食补充柠檬酸盐可以促进长寿

饲喂高脂肪饮食的小鼠在补充柠檬酸盐或酮体β-羟基丁酸盐(βOHB)后也显示出代谢健康和记忆的改善。