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JAMA Surg：一般人群术后谵妄不会导致预后认知不良

2019-01-21 zhangfan MedSci原创

谵妄认知老年人
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研究认为，一般人群术后谵妄与不良认知预后无关

老年患者术后谵妄与长期认知功能下降有关，近日研究人员考察了年轻和多种族人群术后谵妄与长期认知能力下降之间的关系。

191名，择期非急诊手术患者参与研究，患者至少住院1夜， 135例(70.7%)患者完成90天随访评估。采用混淆评定法(CAM)对患者术后24-72小时首次谵妄进行评估。研究的主要终点为术后90天认知较基线变化。

患者平均年龄56.8岁，女性占57.6%。研究发现，术后谵妄人群90天T-MoCA得分略微上升（谵妄vs非谵妄，0.69 vs 0.67）。多因素调整后发现，术前认知障碍是唯一值得注意的混杂因素，当对术前认知障碍进行调整时，术后谵妄人群T-MoCA得分进一步降低（谵妄vs非谵妄，0.16 vs 0.67）

研究认为，一般人群术后谵妄与不良认知预后无关。

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    2019-07-01 小微940490

    mark

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=368788, encodeId=9cb3368e887e, content=mark, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=526e2567988, createdName=小微940490, createdTime=Mon Jul 01 22:15:45 CST 2019, time=2019-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307302, encodeId=506f130e302a7, content=<a href='/topic/show?id=2fbb61104e6' target=_blank style='color:#2F92EE;'>#术后谵妄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61104, encryptionId=2fbb61104e6, topicName=术后谵妄)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5462342, createdName=sunmin0219, createdTime=Wed Jan 23 05:08:00 CST 2019, time=2019-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358826, encodeId=793d358826cd, content=好 , beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/01/21/7cfc301d2b25f46e0ce3ec70d67e671c.jpg, createdBy=2eaf2535638, createdName=1250ebb1m37(暂无昵称), createdTime=Mon Jan 21 19:15:54 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358809, encodeId=2e9235880915, content=好文，值得点赞！认真学习，应用于实践！谢谢分享给广大同好！, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 21 14:52:47 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
    2019-01-23 sunmin0219

    #术后谵妄#

    0

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    2019-01-21 1250ebb1m37(暂无昵称)

    好

    0

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    2019-01-21 ylzr123

    好文，值得点赞！认真学习，应用于实践！谢谢分享给广大同好！

    0

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