Medicine:研究发现幽门螺杆菌感染会促进亚洲人群非酒精性脂肪肝的进展

2020-09-28 MedSci原创 MedSci原创

目前尚未清楚幽门螺杆菌感染是否能促进非酒精性脂肪肝(NAFLD)的发生和发展。本研究旨在通过整合所有现有数据,评估幽门螺杆菌感染与非酒精性脂肪肝之间的确切关系,研究结果已在线发表于。

目前尚未清楚幽门螺杆菌感染是否能促进非酒精性脂肪肝(NAFLD)的发生和发展。本研究旨在通过整合所有现有数据,评估幽门螺杆菌感染与非酒精性脂肪肝之间的确切关系,研究结果已在线发表于Medicine。

通过检索PubMed、Embase、Web of Science、Scopus、中国国家知识基础设施、万方等数据库,收集有关幽门螺杆菌感染与NAFLD的文章。采用随机效应模型进行数据分析,然后进行亚组分析和元回归,探索异质性来源。

 

结果,共有21篇文章被纳入研究。汇总分析显示,幽门螺杆菌感染促进了NAFLD的发生。亚组分析和回归分析显示,病例-对照比可能是异质性的来源之一。

综上所述,该研究结果表明,幽门螺杆菌感染是促进亚洲人群非酒精性脂肪肝进展的因素之一。这为非酒精性脂肪肝的临床预防和治疗提供了新的方法。

 

原始出处:

 

Rongqiang LiuQiuli Liu, et al., Association between Helicobacter pylori infection and nonalcoholic fatty liver: A meta-analysis. Medicine (Baltimore). 2019 Nov;98(44):e17781. doi: 10.1097/MD.0000000000017781.

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    2020-10-18 kalseyzl
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    2020-10-02 jeanqiuqiu
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    2021-03-07 kcb069
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