Stroke:卒中病因学会改变急性卒中患者的血管内治疗效果

2019-12-23 xing.T MedSci原创

由此可见,这些结果提供了与非心脏栓塞性LVO相比,心脏栓塞性LVO患者接受血管内治疗更有效的证据。

卒中病因会促进血栓的形成。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员假设血管内治疗在心脏栓塞和非心脏栓塞大血管闭塞(LVO)患者中得到不同的疗效。

研究人员比较了来自GSR-ET(德国卒中登记-血管内治疗;n=2589)试验的心脏栓塞性和非心脏栓塞性LVO患者的手术特征、再灌注等级和出院后90天的功能结局。为了确定其与功能结局的关联,研究人员使用有序多变量Logistic回归模型计算校正后的比值比和95%CI,并校正了潜在的基线混杂变量。

与非心脏栓塞性LVO相比,单次血栓切除术后,心脏栓塞性LVO患者的血管内治疗成功再灌注率(85.6% vs. 81.0%;P=0.002)和完全再灌注率(45.7% vs. 38.1%;P<0.001)更高。心脏栓塞性LVO患者出院时(调整后的比值比为1.61 [95%CI为1.37-1.88])和90天(调整后的比值比为1.29 [95%CI为1.09-1.53])具有更好的功能结局。在介导分析中,再灌注解释了病因学对出院时功能结局的影响的47%。

由此可见,这些结果提供了与非心脏栓塞性LVO相比,心脏栓塞性LVO患者接受血管内治疗更有效的证据。

原始出处:

Steffen Tiedt.et al.Stroke Etiology Modifies the Effect of Endovascular Treatment in Acute Stroke.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.028383

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    2019-12-24 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2019-12-24 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2019-12-24 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0