Stroke:胃肠道疾病与首次缺血性卒中风险之间的关系

2020-10-12 MedSci原创 MedSci原创

在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。

最近的研究表明,肠道微生物组的改变会导致动脉粥样硬化负担和血管疾病。尽管已知许多胃肠道疾病会破坏人类正常肠道微生物群组,但胃肠道疾病对随后的脑血管疾病临床结局的影响仍未明确。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员进行了一项探索性分析,以评估胃肠道疾病与缺血性卒中之间的关系。

研究人员进行了一项回顾性队列研究,使用了2008年至2015年期间全国范围内医疗受益人样本,仅纳入了66岁及以上的受益人。研究人员使用先前验证的诊断代码来确定缺血性卒中的主要结局。研究人员根据解剖位置、疾病慢性程度和疾病机制对胃肠道疾病进行了分类。研究人员使用Cox比例风险模型评估了胃肠道疾病类别与缺血性卒中之间的相关性,并调整了人口统计学和已知的血管危险因素。

每个分析中平均有1725246名受益人,在对已知的卒中危险因素进行调整后,几种胃肠道疾病与缺血性卒中的风险增加相关。最显著的正相关包括胃部疾病(风险比为1.17 [95%CI为1.15-1.19]和功能性胃肠道疾病(1.16 [95%CI为1.15-1.17])、炎症性胃肠道疾病(1.13 [95%CI为1.12-1.15])和感染性胃肠道疾病(1.13 [95%CI为1.12-1.15])。相反,研究人员发现肛门和直肠疾病(0.97 [95%CI为0.94–1.00])或肿瘤性胃肠道疾病(0.97 [95%CI为0.94–1.00])与卒中之间没有关联。

由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。

原始出处:

William H. Roth,et al.Gastrointestinal Disorders and Risk of First-Ever Ischemic Stroke.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030643

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createdName=12498da4m32(暂无昵称), createdTime=Sun Jun 20 20:02:21 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1666231, encodeId=a0cb166623158, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=960826051850, createdName=xxxx1058, createdTime=Thu Feb 25 22:02:21 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909332, encodeId=9ebc909332f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=01a15441554, createdName=燃烧的火柴, createdTime=Sat Dec 19 10:50:00 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281349, encodeId=82e51281349b2, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346332, encodeId=dea01346332af, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
    2020-12-19 燃烧的火柴

    了解

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1893329, encodeId=b77c189332986, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Mar 22 19:02:21 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806405, encodeId=8d05180640544, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Sun Jun 20 20:02:21 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1666231, encodeId=a0cb166623158, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=960826051850, createdName=xxxx1058, createdTime=Thu Feb 25 22:02:21 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909332, encodeId=9ebc909332f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=01a15441554, createdName=燃烧的火柴, createdTime=Sat Dec 19 10:50:00 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281349, encodeId=82e51281349b2, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346332, encodeId=dea01346332af, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1893329, encodeId=b77c189332986, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Mar 22 19:02:21 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806405, encodeId=8d05180640544, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Sun Jun 20 20:02:21 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1666231, encodeId=a0cb166623158, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=960826051850, createdName=xxxx1058, createdTime=Thu Feb 25 22:02:21 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909332, encodeId=9ebc909332f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=01a15441554, createdName=燃烧的火柴, createdTime=Sat Dec 19 10:50:00 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281349, encodeId=82e51281349b2, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346332, encodeId=dea01346332af, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1893329, encodeId=b77c189332986, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Mar 22 19:02:21 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806405, encodeId=8d05180640544, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Sun Jun 20 20:02:21 CST 2021, time=2021-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1666231, encodeId=a0cb166623158, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=960826051850, createdName=xxxx1058, createdTime=Thu Feb 25 22:02:21 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909332, encodeId=9ebc909332f6, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=01a15441554, createdName=燃烧的火柴, createdTime=Sat Dec 19 10:50:00 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281349, encodeId=82e51281349b2, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346332, encodeId=dea01346332af, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1893329, encodeId=b77c189332986, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Mar 22 19:02:21 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806405, encodeId=8d05180640544, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, 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topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
    2020-10-13 咻凡

    在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1893329, encodeId=b77c189332986, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Mar 22 19:02:21 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806405, encodeId=8d05180640544, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, 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createdName=燃烧的火柴, createdTime=Sat Dec 19 10:50:00 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281349, encodeId=82e51281349b2, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346332, encodeId=dea01346332af, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
    2020-10-13 Lexi

    由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。

    0

  10. 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topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540642, encodeId=8c821540642e7, content=<a href='/topic/show?id=e1f281e045e' target=_blank style='color:#2F92EE;'>#肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81704, encryptionId=e1f281e045e, topicName=肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d5513274388, createdName=guozhenyu, createdTime=Wed Oct 14 11:02:21 CST 2020, time=2020-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891774, encodeId=e5da891e74f5, content=在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Oct 13 15:03:11 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=891740, encodeId=0a84891e40e0, content=由此可见,在调整了人口统计学特征和已知的卒中危险因素后,有些胃肠道疾病与未来缺血性卒中的风险增加相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae205385871, createdName=Lexi, createdTime=Tue Oct 13 11:25:45 CST 2020, time=2020-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026700, encodeId=ab5d1026e00eb, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Oct 12 23:02:21 CST 2020, time=2020-10-12, status=1, ipAttribution=)]
    2020-10-12 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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