Cardiovasc Res :中国房颤患病率居世界前列!PURE研究新分析

2020-08-14 朱朱 文韬 中国循环杂志

近日发表的一项基于PURE研究全球20个国家的最新分析表明,在全球不同地区,年龄和性别标化的房颤患病率可相差12倍。研究发现,北美、欧洲、中国、东南亚最高(270-360例/10万).

近日发表的一项基于PURE研究全球20个国家的最新分析表明,在全球不同地区,年龄和性别标化的房颤患病率可相差12倍。研究发现,北美、欧洲、中国、东南亚最高(270-360例/10万);高收入国家、中等收入国家的房颤患病率分别是低收入国家的11倍和7倍。

PURE研究观察到,在校正性别、年龄、身高、体重、收缩压、舒张压、心力衰竭、心肌梗死糖尿病、抗高血压药物、目前吸烟者和收入阶层后,中国和东南亚的房颤患病率全球最高,但这不能用危险因素来解释。

近期,中国、以色列、加拿大研究人员对2017年全球疾病负担研究195个国家和地区的数据进行分析后发现,2017年全球有3757万例房颤患者,新发房颤305万例,28.7万人因房颤死亡。

总体上,男士中房颤新发病例多于女士,分别为159万例和146万例,但女士中因房颤死亡的例数多于男士(分别为17.7万例和11.0万例)。

75~79岁是房颤患病率最高的年龄段,65~69岁则是房颤发病率最高的年龄段,85~89岁是房颤死亡率最高的年龄段。

在社会人口指数(SDI)较高即相对发达的国家中,年龄标化的房颤患病率、发病率、死亡率均较高,其中新西兰和美国的房颤患病率和发病率最高。

从1990年至2017年,全球房颤患病人数增加了1843例,新发病例增加了145万例,房颤死亡人数增倍。

但是,近30年全球年龄标化的房颤死亡率维持稳定,房颤患病率和发病率则分别降低了5.1%和4.3%。

研究者认为,这在一定程度与人口增长和老龄化有关。另外,由于房颤筛查新技术的应用,越来越多的无症状患者被发现。其他因素还包括:房颤知晓率提高、有效的房颤治疗措施较少。

发达国家中年龄标化的房颤患病率、发病率、死亡率均有所降低,但SDI中等国家中年龄标化的房颤患病率和发病率增幅最大,分别升高4.9%和5.1%,不发达国家中年龄标化的房颤死亡率增幅最大,升高了15.9%。

在各种危险因素中,高血压是导致房颤死亡的首要因素,占34.3%,其次是超重和肥胖(20.7%)和饮酒(9.4%)。

在女士中,高血压和超重或肥胖是导致房颤死亡的主要原因,而在男士中,饮酒、吸烟和铅暴露的影响更大。

从1990年至2017年,在房颤死亡相关的危险因素中,高血压、饮酒、吸烟的影响有减小的趋势,而超重或肥胖、高盐饮食、铅暴露的影响则在增大。

原始出处:

Philip G Joseph, Jeffrey S Healey, Parminder Raina, et al. Global variations in the prevalence, treatment, and impact of atrial fibrillation in a multi-national cohort of 153,152 middle-aged individuals. Cardiovasc Res. 2020 Aug 10;cvaa241. doi: 10.1093/cvr/cvaa241.

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    2021-03-06 quxin068
  2. [GetPortalCommentsPageByObjectIdResponse(id=1939103, encodeId=b26119391036c, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Mar 06 19:56:27 CST 2021, time=2021-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250705, encodeId=91431250e05ee, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sun Aug 16 01:56:27 CST 2020, time=2020-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=809051, encodeId=5ed0809051d4, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Sat Aug 15 06:10:59 CST 2020, time=2020-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031294, encodeId=96d6103129421, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Aug 14 13:56:27 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808883, encodeId=4a2580888391, content=<a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>中国的患病率跟其他新馆疾病一样都排在前面。, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Fri Aug 14 12:00:59 CST 2020, time=2020-08-14, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1939103, encodeId=b26119391036c, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Mar 06 19:56:27 CST 2021, time=2021-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250705, encodeId=91431250e05ee, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sun Aug 16 01:56:27 CST 2020, time=2020-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=809051, encodeId=5ed0809051d4, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Sat Aug 15 06:10:59 CST 2020, time=2020-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031294, encodeId=96d6103129421, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Aug 14 13:56:27 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808883, encodeId=4a2580888391, content=<a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>中国的患病率跟其他新馆疾病一样都排在前面。, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Fri Aug 14 12:00:59 CST 2020, time=2020-08-14, status=1, ipAttribution=)]
    2020-08-15 1581f8c42cm

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1939103, encodeId=b26119391036c, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Mar 06 19:56:27 CST 2021, time=2021-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250705, encodeId=91431250e05ee, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sun Aug 16 01:56:27 CST 2020, time=2020-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=809051, encodeId=5ed0809051d4, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200814/81d08245657a4a7f9a1ef713c0ec5878/ec4b201a22194a319b1aeb171bc6bb3d.jpg, createdBy=41e02111625, createdName=1581f8c42cm, createdTime=Sat Aug 15 06:10:59 CST 2020, time=2020-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031294, encodeId=96d6103129421, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Aug 14 13:56:27 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808883, encodeId=4a2580888391, content=<a href='/topic/show?id=737a54248f5' target=_blank style='color:#2F92EE;'>#房颤#</a>中国的患病率跟其他新馆疾病一样都排在前面。, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54248, encryptionId=737a54248f5, topicName=房颤)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Fri Aug 14 12:00:59 CST 2020, time=2020-08-14, status=1, ipAttribution=)]
    2020-08-14 心介

    房颤,临床上碰到很多哦

    0

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    2020-08-14 lovetcm

    #房颤#中国的患病率跟其他新馆疾病一样都排在前面。

    0

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