JACC:血流储备分数的应用可以降低稳定性心绞痛患者的远期死亡风险

2020-06-09 MedSci原创 MedSci原创

冠脉内导丝测量的分流量储备(FFR)为经皮冠脉介入(PCI)手术的决策提供了依据,然而,关于FFR对稳定型心绞痛患者长期临床转归的影响的资料有限。本研究的目的是确定在接受PCI的稳定型心绞痛患者中,F

冠脉内导丝测量的分流量储备(FFR)为经皮冠脉介入(PCI)手术的决策提供了依据,然而,关于FFR对稳定型心绞痛患者长期临床转归的影响的资料有限。本研究的目的是确定在接受PCI的稳定型心绞痛患者中,FFR的使用与全因死亡率之间的关系。

本研究纳入分析了来自瑞典SCAAR注册数据库中的接受PCI治疗的稳定性心绞痛患者,主要终点事件是全因死亡率,次要终点事件是支架内血栓或再狭窄。最终,共纳入分析23860名接受PCI治疗的稳定性心绞痛患者,其中有3367名患者采用了FFR指导策略。经过平均4.7年时间的随访,FFR组的患者全因死亡率更低(HR: 0.81; 95% [CI]: 0.73-0.89; p < 0.001),支架内血栓和再狭窄风险也更低。另外,两组患者之间的围手术期并发症发生率无明显差异。

研究结果显示,对于稳定性心绞痛患者,PCI过程中的FFR使用可以降低患者远期的全因死亡率和支架内血栓或再狭窄风险。

原始出处:

Sebastian V et al.Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance.JACC.2020 June.

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    2020-08-17 hbwxf
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