Alzheimer&Dementia:各族裔群体的痴呆症发病率、诊断年龄和生存率

2022-09-10 MedSci原创 MedSci原创

据预测,2019年至2050年期间,全世界的痴呆症患者人数将从5700万上升到1.5亿以上。

据预测,2019年至2050年期间,全世界的痴呆症患者人数将从5700万上升到1.5亿以上。英国约有13%的人口为少数民族;最大的非白人群体是南亚人(5.3%),第二大群体是黑人(非洲或加勒比海人-3.4%)。亚洲组由南亚或东亚血统的人组成。后者与白人相比,患痴呆症的风险较低。

近期,来自英国伦敦大学的学者调查了被诊断为痴呆症的发病率,以及诊断时的年龄和诊断后的存活率在英国三个最大的种族群体中是否有差异,结果发表在Alzheimer&Dementia杂志上。

研究人员使用初级保健电子健康记录、链接的医院插曲统计和年龄≥65岁的成年人的死亡数据,比较了1997-2018年记录的白人、南亚人和黑人的痴呆症发病率、诊断时的年龄、生存时间和诊断后死亡的年龄。

结果显示,黑人的痴呆症发病率较高(IRR=1.22,95%CI 1.15-1.30)。南亚裔和黑人痴呆症患者的死亡年龄比白人低(南亚裔参与者的平均差异为-2.97年,(95% CI -3.41至-2.53);黑人参与者的平均差异为-2.66年,(95% CI -3.08至-2.24)。

综上,南亚裔和黑人的诊断和死亡年龄较小,这意味着针对这些群体的有针对性的预防和护理策略应被优先考虑,并为其量身定做,以促进其采纳。

 

 

参考文献:

Incidence, age at diagnosis and survival with dementia across ethnic groups in England: A longitudinal study using electronic health records. https://doi.org/10.1002/alz.12774

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    2023-04-05 xjy13
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    2023-05-01 Boyinsh
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