JCEM:一年跨性别激素治疗后变性人乳房发育情况

2017-11-21 MedSci MedSci原创

众所周知乳房是女性化的重要标志之一,因此对于变性人(男性到女性的变性人)而言相当重要。但是,目前关于在初始跨性别激素治疗(CHT)之后乳房什么时候开始发育及能发育至何程度还尚未可知。2017年11月20日在JCEM杂志上发表的一篇文章则旨在探讨变性人在CHT第一年间乳腺发育及罩杯大小的变化,以及是否存在临床或实验室的参数可以估计乳腺发育情况。

众所周知乳房是女性化的重要标志之一,因此对于变性人(男性到女性的变性人)而言相当重要。但是,目前关于在初始跨性别激素治疗(CHT)之后乳房什么时候开始发育及能发育至何程度还尚未可知。2017年11月20日在JCEM杂志上发表的一篇文章则旨在探讨变性人在CHT第一年间乳腺发育及罩杯大小的变化,以及是否存在临床或实验室的参数可以估计乳腺发育情况。

Christel Josefa Maria de Blok等人进行了一项前瞻性的多中心队列研究,所有完成第一年CHT治疗的变性人(n=229)纳入研究,以厘米和罩杯来评估乳腺的发育。

纳入变性人的中位年龄是为28岁(范围18;69岁)。研究结果显示平均乳腺-胸差值从基线的4.1±2.9cm上升到CHT一年后的7.9±3.1cm,主要造成小于AAA罩杯(48.7%)。主要的乳房发育在治疗的前6个月发生。血清雌二醇水平并不能预测CHT治疗一年后的乳房发育水平(第一四分位数:+3.6cm(95%CI +2.7cm;4.5cm),第二四分位数:+3.2cm(95% CI 2.3;4.2cm),第三四分位数:+4.4cm(95% CI 3.5;5.3cm),第四四分位数:+3.6cm(95% CI 2.7;4.5cm))。

该研究表明一年CHT治疗后乳房发育是适度的,主要发生在前6个月。目前尚未发现预测乳腺发育的临床或实验室参数。

原始出处:


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    2018-09-19 achengzhao
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    2017-11-25 smallant2015
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    2017-11-23 neurowu
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    2017-11-23 huangdf
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