Lancet Public Health :澳研究称医用大麻不一定能减轻慢性非癌性疼痛

2018-07-09 陈善辉 新华网

澳大利亚研究人员在最新一期英国《柳叶刀·公共卫生》上发表报告称,医用大麻不一定能减轻慢性非癌性疼痛。

澳大利亚研究人员在最新一期英国《柳叶刀·公共卫生》上发表报告称,医用大麻不一定能减轻慢性非癌性疼痛。

阿片类药物包括可卡因、美沙酮、吗啡等,主要用于治疗疼痛,但反复使用易使人成瘾。世界上越来越多的人正在尝试使用医用大麻来治疗慢性非癌性疼痛。但医用大麻能减少阿片类药物用量只是一种猜测,医学界一直缺乏有说服力的实验证据。

澳大利亚全国药物和酒精研究中心等机构的研究人员在社区药房招募了1514名慢性非癌性疼痛患者,每年评估其疼痛病症、健康状况以及药物和医用大麻使用情况。这些人平均疼痛时间为10年,平均服用处方阿片类药物治疗疼痛的时间为4年。4年后,约80%的人完成了每项评估。

结果显示,与其他人相比,使用医用大麻的人在一系列评估报告中称,他们感到更疼和更不安,日常生活更不便,医用大麻缓解疼痛的效果并不佳。这表明,医用大麻并不一定能帮助减少患者的疼痛与不安程度,也无助于减少阿片类药物使用剂量。

澳大利亚全国药物和酒精研究中心的加布丽埃尔·坎贝尔说:“慢性非癌性疼痛是一个复杂的问题。对于大多数人来说,不太可能有一种有效的治疗方法。关于使用医用大麻可以缓解患者疼痛或减少阿片类药物的使用的说法,我们并未发现有力的证据。”

原始出处:

Gabrielle Campbell, Wayne D Hall, Amy Peacock, et.al. Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study. The Lancet Public Health Volume 3, No. 7, e341–e350, July 2018

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    2019-03-22 howi
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    2018-10-18 shizhenshan
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    2018-07-11 kcb069
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