JAMA:医生对ICU患者生存和功能的预测准确吗?

2017-05-22 MedSci MedSci原创

重要性:长期生存率和功能预后的预测影响医务人员对危重病人的治疗策略,但其准确性依然鲜为人知。目的:本研究的目的是探讨ICU(重症监护病房)医生和护士对患者6个月后发病率和死亡率(包括活动能力、如厕能力,以及认知)认知预测的准确性。设计,设置和参与者:这是一项前瞻性队列研究,在美国宾夕法尼亚,费城的3家医院的5个ICU进行,2013年10月到2014年5月在ICU接受至少为期3天的患者被纳入研究,同

重要性:长期生存率和功能预后的预测影响医务人员对危重病人的治疗策略,但其准确性依然鲜为人知。

目的:本研究的目的是探讨ICU(重症监护病房)医生和护士对患者6个月后发病率和死亡率(包括活动能力、如厕能力,以及认知)认知预测的准确性。

设计,设置和参与者:这是一项前瞻性队列研究,在美国宾夕法尼亚,费城的3家医院的5个ICU进行,2013年10月到2014年5月在ICU接受至少为期3天的患者被纳入研究,同时这些患者接受了机械通气或血管升压药治疗,或两者均接受。研究参与者也包括这些患者的主治医生和床边护士。随访于2014年12月完成。

主要终点和措施:ICU医生和护士的二元预测包括,住院死亡率和6个月结果(包括死亡率,返回原居住地,独立如厕的能力,独立爬10楼的能力,记忆、思考、解决日常问题的能力[即认知正常])。对于每个结果,医生和护士使用李克特量表的五分量表法对患者的预后进行了一个二元的预测。通过随访幸存患者或其家属对结果进行评估。采用阳性和阴性似然比(LR),C统计量及其它操作特性确定预测的准确性。

结果:研究人员共检测到340例患者符合条件的患者,其中303(89%)被纳入研究(中位年龄:62岁[四分位差,53-71];57%为男性;32%是非洲裔美国人);共随访了299(99%)名患者,其中169(57%)名存活。47名医生和128名护士参与了研究并做出预测。

医生预测最准确的是6个月的死亡率(阳性LR,5.91 [ 95% CI,3.74-9.32 ];阴性LR,0.41 [ 95% CI,0.33-0.52 ];C统计量,0.76 [ 95% CI,0.72-0.81 ]);预测最不准确的是认知(阳性LR,2.36 [ 95% CI,1.36-4.12 ];阴性LR,0.75 [ 95% CI,0.61-0.92 ];C统计量,0.61 [ 95% CI,0.54-0.68 ])。

护士预测最准确的是住院死亡率(阳性LR,4.71 [ 95% CI,2.94-7.56 ];阴性LR,0.61 [ 95% CI,0.49-0.75 ];C统计量,0.68 [ 95% CI,0.62-0.74 ]);预测最不准确的也是认知(阳性LR,1.50 [ 95% CI,0.86-2.60 ];阴性LR,0.88 [ 95% CI,0.73-1.06 ];C统计量,0.55 [ 95% CI,0.48-0.62 ])。

当医生和护士都对预测有信心时,预测的准确性较高(如,对6个月死亡率预测有信心的医生的预测准确性:阳性LR,33.00[ 95% CI,8.34-130.63 ];阴性LR,0.18 [ 95% CI,0.09-0.35 ];C统计量,0.90 [ 95% CI,0.84-0.96 ])。与一个含有客观临床变量的预测模型相比,这个还包括医生和护士预测的模型对祝愿死亡率、6个月死亡率及返回原居住地的预测具有较高的准确性(P值均 < 0.01)。

结论:ICU医生和护士的对危重患者的6个月结局的预测的准确性是多样的,且取决于预测的项目和其对预测的信心。为了更好地了解临床医生对长期结果的预测估计情况需要进一步的研究。

原始出处:


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    2017-05-23 穆慕仁真

    在评估基础上的判断

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1932573, encodeId=091319325e3b7, content=<a href='/topic/show?id=5cd95305803' target=_blank style='color:#2F92EE;'>#患者生存#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53058, encryptionId=5cd95305803, topicName=患者生存)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=47c5349, createdName=tastas, createdTime=Sun Jul 02 15:47:00 CST 2017, time=2017-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595349, encodeId=68df1595349dd, content=<a href='/topic/show?id=44b993e977' target=_blank style='color:#2F92EE;'>#ICU患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9379, encryptionId=44b993e977, topicName=ICU患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=003c18235152, createdName=piaojinhua, createdTime=Wed May 24 08:47:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201487, encodeId=d02120148e85, content=在评估基础上的判断, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/MnthNYiaYT4SNKeEmLuaew8INxnWjegguR2tEB5XL37oicS1HFZDejzeXjjFpdPVZ2VaLzXibdTXkkPRuj4YVQkTg/132, createdBy=76cb105999, createdName=穆慕仁真, createdTime=Tue May 23 06:27:31 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201433, encodeId=00da2014334b, content=经验和职业素养很重要,个人认为。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Tue May 23 02:33:55 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201385, encodeId=7f1b20138568, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4KDsF1g1gUHzGM0LHxX5B5uhEMln8y8iagso9N4XBTQVPmHrCNoT3o8bw80Ds53TpTgcPnKUIfkyw/0, createdBy=bc101976400, createdName=suibian2007bbb, createdTime=Tue May 23 00:21:11 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201327, encodeId=1f2c20132e3c, content=也是猜测, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon May 22 21:43:35 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201317, encodeId=3f4f20131e09, content=感谢梅斯医学,受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhbPwBo0yCebU4qpdSwzpBA1WFXMEUicoTnJDickpj9Ve1cUdNjjTiaDXmpXL47LYh3DdYkPOA2kddyZ/0, createdBy=508c2054450, createdName=solarjin, createdTime=Mon May 22 20:33:47 CST 2017, time=2017-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201305, encodeId=1f5120130501, content=icu医生的管理很重要, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4a622063382, createdName=xzp19850, createdTime=Mon May 22 18:32:46 CST 2017, time=2017-05-22, status=1, ipAttribution=)]
    2017-05-23 189****7206

    经验和职业素养很重要,个人认为。

    0

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    2017-05-23 suibian2007bbb

    学习

    0

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    2017-05-22 Y—xianghai

    也是猜测

    0

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    2017-05-22 solarjin

    感谢梅斯医学,受教了

    0

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    2017-05-22 xzp19850

    icu医生的管理很重要

    0

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