JACC:标准化治疗可改善心源性休克预后

2019-04-15 不详 MedSci原创

心源性休克(CS)是一种多因素的血流动力学复杂的综合征,死亡率高。尽管在再灌注和机械循环支持方面取得了进展,但CS的治疗方法仍然存在很大的差异,且效果不佳。本研究的目的旨在评估以团队为基础的标准化方法是否可以改善CS的预后。本研究纳入分析了204名CS患者,并对患者的CS病因、人口统计学特征、右心导管插入术、机械循环支持使用和生存率进行了统计,在基线水平和CS诊断后24小时测量了患者的心输出功率(

心源性休克(CS)是一种多因素的血流动力学复杂的综合征,死亡率高。尽管在再灌注和机械循环支持方面取得了进展,但CS的治疗方法仍然存在很大的差异,且效果不佳。本研究的目的旨在评估以团队为基础的标准化方法是否可以改善CS的预后。

本研究纳入分析了204名CS患者,并对患者的CS病因、人口统计学特征、右心导管插入术、机械循环支持使用和生存率进行了统计,在基线水平和CS诊断后24小时测量了患者的心输出功率(CPO)和肺动脉搏动指数(PAPI)。分析结果显示,相比于2016年47%的30天生存率,2017年和2018年的30天生存率增至57.9%和76.6%(p < 0.01),30天死亡率的独立预测因子为年龄≥71岁、糖尿病、血透、乳酸盐水平≥3.0 mg/dl、CPO <0.6 W和诊断后24h PAPi <1.0。

本研究结果显示,以团队为基础的标准化方法可以提高心源性休克的预后,结合人口统计学、实验室和血流动力学数据的评分可用于量化风险,并指导临床决策对所有类型的心源性休克。

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    2019-10-19 hbwxf
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    2019-04-17 mhm295

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