JACC:经导管主动脉瓣置换术后感染性心内膜炎的远期发生率研究

2019-04-12 不详 MedSci原创

接受外科主动脉瓣置换术(SAVR)后的患者发生感染性心内膜炎(IE)的风险会更高,然而经导管主动脉瓣置换术(TAVR)后的IE发生风险尚不清楚。本研究纳入分析了丹麦国家数据库中的2632名接受TAVR治疗和3777名接受SAVR治疗的无IE病史的患者,经过平均3.6年时间的随访,4.4%的TAVR组患者和4.9%的SAVR组患者出现感染性心内膜炎,两组患者从手术到IE住院之间的平均时间间隔分别为3

接受外科主动脉瓣置换术(SAVR)后的患者发生感染性心内膜炎(IE)的风险会更高,然而经导管主动脉瓣置换术(TAVR)后的IE发生风险尚不清楚。

本研究纳入分析了丹麦国家数据库中的2632名接受TAVR治疗和3777名接受SAVR治疗的无IE病史的患者,经过平均3.6年时间的随访,4.4%的TAVR组患者和4.9%的SAVR组患者出现感染性心内膜炎,两组患者从手术到IE住院之间的平均时间间隔分别为352天和625天。TAVR组和SAVR组患者的1年IE累积风险分别是2.3%和1.8%,5年IE累积风险分别为5.8%和5.1%。在多元回归分析模型中,TAVR组患者的IE发生风险与SAVR组无明显差异。

研究结果显示,经导管主动脉瓣置换术后患者5年的感染性心内膜炎发生率为5.8%,与外科主动脉瓣置换术后患者无明显差异。

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    2019-12-10 hbwxf
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encryptionId=39cae96626f, topicName=置换)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3a7c35056336, createdName=yxch48, createdTime=Fri Jun 28 21:51:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1655451, encodeId=01a81655451dd, content=<a href='/topic/show?id=7c2853311ac' target=_blank style='color:#2F92EE;'>#感染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53311, encryptionId=7c2853311ac, topicName=感染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Thu Oct 24 21:51:00 CST 2019, time=2019-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326179, encodeId=450013261e9b0, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332639, encodeId=a647133263981, content=<a href='/topic/show?id=1dd6231822d' target=_blank style='color:#2F92EE;'>#主动脉瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350724, encodeId=2a7f1350e245c, content=<a href='/topic/show?id=a32d508e8c3' target=_blank style='color:#2F92EE;'>#心内膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50878, encryptionId=a32d508e8c3, topicName=心内膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367171, encodeId=aec4136e171b7, content=<a href='/topic/show?id=b6222320322' target=_blank style='color:#2F92EE;'>#主动脉瓣置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23203, encryptionId=b6222320322, topicName=主动脉瓣置换术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b24249, createdName=medsci246, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415505, encodeId=3949141550556, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=)]
    2019-06-28 yxch48
  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415505, encodeId=3949141550556, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 14 00:51:00 CST 2019, time=2019-04-14, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1826520, encodeId=aa0b1826520b4, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Tue Oct 29 22:51:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854358, encodeId=ca421854358d6, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, 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  7. 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