Eur Urol Oncol:前列腺活检更佳方法的选择

2021-04-25 AlexYang MedSci原创

虽然磁共振成像(MRI)-靶向活检(TBx)相对于系统性活检(SBx)能更好地检测前列腺癌(PCa),但相对于单独的Bx方法,两种方法的结合能提高临床显著PCa的检测。然而,联合Bx要让患者接受更多的

虽然磁共振成像(MRI)-靶向活检(TBx)相对于系统性活检(SBx)能更好地检测前列腺癌(PCa),但相对于单独的Bx方法,两种方法的结合能提高临床显著PCa的检测。然而,联合Bx要让患者接受更多的活检核心,并对临床上不显著的PCa进行更多的检测。

最近,有研究人员确定了活检前的前列腺MRI是否可以确定哪些男性可以放弃联合Bx而不存在遗漏临床显著PCa(csPC)的风险

研究人员对具有MRI可见的前列腺病变的男性进行了TBx和SBx的联合检查。研究的主要结果是TBx和SBx对≥2级和≥3级PCa的检出率,并按前列腺成像-报告和数据系统(PI-RADS)评分进行分层。结果发现,在PI-RADS 5 病例中,几乎所有的csPCs都是通过TBx检测出来的,因为增加SBx后,只检测到2.5%的GG≥2的癌症。然而,在PI-RADS 3-4病例中,增加SBx检测到的csPCs大大多于单独的TBx(7.5% vs 8%)。相反,相对于SBx(7.8%),TBx对PI-RADS 2病变男性中csPC的检测增加不多(2%)。

PI-RADS的癌症检出率和活检方法

最后,研究人员指出,虽然联合Bx增加了MRI可见前列腺病变男性的csPC检测,但这种效果主要限于PI-RADS 3-4病变对PI-RADS 5的男性采用TBx,对PI-RADS 3-4的男性采用联合Bx的策略,可以避免对有PI-RADS 5病变的男性进行过多的活检,同时降低了csPC遗漏风险(1%)

原始出处:

Michael Ahdoot , Amir H Lebastchi , Lori Long et al. Using Prostate Imaging-Reporting and Data System (PI-RADS) Scores to Select an Optimal Prostate Biopsy Method: A Secondary Analysis of the Trio Study. Eur Urol Oncol. Apr 2021

 

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    2021-09-06 minlingfeng
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    2021-05-13 ms4000000681655625

    MRI对于提高CS的PCa检出有用

    0

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    2021-05-04 ms8000000273684330

    感谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2046047, encodeId=afa7204604ede, content=<a href='/topic/show?id=e5713251390' target=_blank style='color:#2F92EE;'>#前列腺活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32513, encryptionId=e5713251390, topicName=前列腺活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Fri Nov 12 14:11:29 CST 2021, time=2021-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1866052, encodeId=4a8a1866052bb, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Sep 06 08:11:29 CST 2021, time=2021-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965278, encodeId=61d19652e8e7, content=MRI对于提高CS的PCa检出有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=86a75470976, createdName=ms4000000681655625, createdTime=Thu May 13 18:03:28 CST 2021, time=2021-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=962615, encodeId=742c96261532, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79ee5485922, createdName=ms8000000273684330, createdTime=Tue May 04 13:25:21 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278226, encodeId=46e312e822699, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Mon Apr 26 15:11:29 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960184, encodeId=32699601840e, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Apr 25 07:15:20 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960176, encodeId=e0599601e633, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210425/188bc6472a1742d09222864964fb4cca/508399781e704ed38acfdf86b724aef5.jpg, createdBy=d0e75483900, createdName=tjlyp, createdTime=Sun Apr 25 06:39:17 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038256, encodeId=762c10382560a, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Sun Apr 25 03:11:29 CST 2021, time=2021-04-25, status=1, ipAttribution=)]
    2021-04-26 smlt2008
  6. [GetPortalCommentsPageByObjectIdResponse(id=2046047, encodeId=afa7204604ede, content=<a href='/topic/show?id=e5713251390' target=_blank style='color:#2F92EE;'>#前列腺活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32513, encryptionId=e5713251390, topicName=前列腺活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Fri Nov 12 14:11:29 CST 2021, time=2021-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1866052, encodeId=4a8a1866052bb, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Sep 06 08:11:29 CST 2021, time=2021-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965278, encodeId=61d19652e8e7, content=MRI对于提高CS的PCa检出有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=86a75470976, createdName=ms4000000681655625, createdTime=Thu May 13 18:03:28 CST 2021, time=2021-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=962615, encodeId=742c96261532, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79ee5485922, createdName=ms8000000273684330, createdTime=Tue May 04 13:25:21 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278226, encodeId=46e312e822699, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Mon Apr 26 15:11:29 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960184, encodeId=32699601840e, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Apr 25 07:15:20 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960176, encodeId=e0599601e633, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210425/188bc6472a1742d09222864964fb4cca/508399781e704ed38acfdf86b724aef5.jpg, createdBy=d0e75483900, createdName=tjlyp, createdTime=Sun Apr 25 06:39:17 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038256, encodeId=762c10382560a, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Sun Apr 25 03:11:29 CST 2021, time=2021-04-25, status=1, ipAttribution=)]
    2021-04-25 学医无涯

    学习一下

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2046047, encodeId=afa7204604ede, content=<a href='/topic/show?id=e5713251390' target=_blank style='color:#2F92EE;'>#前列腺活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32513, encryptionId=e5713251390, topicName=前列腺活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Fri Nov 12 14:11:29 CST 2021, time=2021-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1866052, encodeId=4a8a1866052bb, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Sep 06 08:11:29 CST 2021, time=2021-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965278, encodeId=61d19652e8e7, content=MRI对于提高CS的PCa检出有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=86a75470976, createdName=ms4000000681655625, createdTime=Thu May 13 18:03:28 CST 2021, time=2021-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=962615, encodeId=742c96261532, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79ee5485922, createdName=ms8000000273684330, createdTime=Tue May 04 13:25:21 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278226, encodeId=46e312e822699, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Mon Apr 26 15:11:29 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960184, encodeId=32699601840e, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Apr 25 07:15:20 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960176, encodeId=e0599601e633, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210425/188bc6472a1742d09222864964fb4cca/508399781e704ed38acfdf86b724aef5.jpg, createdBy=d0e75483900, createdName=tjlyp, createdTime=Sun Apr 25 06:39:17 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038256, encodeId=762c10382560a, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Sun Apr 25 03:11:29 CST 2021, time=2021-04-25, status=1, ipAttribution=)]
    2021-04-25 tjlyp

    感谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2046047, encodeId=afa7204604ede, content=<a href='/topic/show?id=e5713251390' target=_blank style='color:#2F92EE;'>#前列腺活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32513, encryptionId=e5713251390, topicName=前列腺活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Fri Nov 12 14:11:29 CST 2021, time=2021-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1866052, encodeId=4a8a1866052bb, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Mon Sep 06 08:11:29 CST 2021, time=2021-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=965278, encodeId=61d19652e8e7, content=MRI对于提高CS的PCa检出有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=86a75470976, createdName=ms4000000681655625, createdTime=Thu May 13 18:03:28 CST 2021, time=2021-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=962615, encodeId=742c96261532, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79ee5485922, createdName=ms8000000273684330, createdTime=Tue May 04 13:25:21 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278226, encodeId=46e312e822699, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Mon Apr 26 15:11:29 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960184, encodeId=32699601840e, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Apr 25 07:15:20 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960176, encodeId=e0599601e633, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210425/188bc6472a1742d09222864964fb4cca/508399781e704ed38acfdf86b724aef5.jpg, createdBy=d0e75483900, createdName=tjlyp, createdTime=Sun Apr 25 06:39:17 CST 2021, time=2021-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1038256, encodeId=762c10382560a, content=谢谢梅斯分享这么多精彩信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=anti-cancer, createdTime=Sun Apr 25 03:11:29 CST 2021, time=2021-04-25, status=1, ipAttribution=)]
    2021-04-25 anti-cancer

    谢谢梅斯分享这么多精彩信息

    0

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