Nat Commun:暴露于火灾中会增加孕妇的流产风险

2021-05-30 xiaozeng MedSci原创

近几十年来,全球各地越来越多地报道了各种明火事件,明火包括多种不同类型,包括野火、山火、煤矿火灾和农业的刀耕火种,其来源与人类活动直接相关或与气候变化间接相关。

近几十年来,全球各地越来越多地报道了各种明火事件,明火包括多种不同类型,包括野火、山火、煤矿火灾和农业的刀耕火种,其来源与人类活动直接相关或与气候变化间接相关。

既往研究显示,明火主要是通过增加环境中危险化学品的暴露来危害人类的健康。生物质燃烧会排放大量有毒的空气污染物,如颗粒物(PM)、多环芳烃和挥发性有机化合物。

据全球估计表明,每年有339,000人过早死亡可归因于暴露于明火烟雾中,导致心肺疾病的风险增加,包括心脏骤停、哮喘、高血压和呼吸道感染因此,了解明火对健康的潜在影响机制对于预防相关疾病负担至关重要。


既往研究证实,明火会损害孕产妇的健康。然而很少有研究分析明火与流产之间的关系。

明火引起PM2.5浓度的时空变化

该研究进行了一项自我比较病例对照研究,包括来自南亚的24,876名母亲,该地区是全球流产负担最重的地区。研究人员使用化学传输模型对火灾PM2.5的浓度进行评估。


结果显示,在怀孕期间,暴露于明火中的火灾PM2.5的平均浓度每增加1微克/立方米,流产事件的调整优势比(OR)约为1.051。相比于非火灾PM2.5,火灾PM2.5与流产的相关性更强。

明火PM2.5与流产之间的关联性分析

综上,该研究结果揭示,暴露于明火会损害孕产妇的健康,并可能导致不可忽视的流产事件的发生。


原始出处:

Xue, T., Geng, G., Han, Y. et al. Open fire exposure increases the risk of pregnancy loss in South Asia. Nat Commun 12, 3205 (28 May 2021).

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1885187, encodeId=a2d4188518e9a, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Oct 31 12:11:52 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2088004, encodeId=6a832088004a3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Nov 04 23:11:52 CST 2021, time=2021-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556987, encodeId=2bdd155698ec5, content=<a href='/topic/show?id=076b66889cf' target=_blank style='color:#2F92EE;'>#火灾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66889, encryptionId=076b66889cf, topicName=火灾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=46ad14842094, createdName=grace5705, createdTime=Tue Jun 01 08:11:52 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969857, encodeId=015196985e32, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK0iclWFtP7WicKXLyVXAOnRibMria0BwB4otV2d2ibbbkZ2XKAvnNH5x3Y1wm9ibMNZZV5ib5qA0B99sMpw/132, createdBy=9a062530214, createdName=yelinlin, createdTime=Mon May 31 14:27:35 CST 2021, time=2021-05-31, status=1, ipAttribution=)]
    2021-10-31 liye789132251
  2. [GetPortalCommentsPageByObjectIdResponse(id=1885187, encodeId=a2d4188518e9a, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Oct 31 12:11:52 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2088004, encodeId=6a832088004a3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Nov 04 23:11:52 CST 2021, time=2021-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556987, encodeId=2bdd155698ec5, content=<a href='/topic/show?id=076b66889cf' target=_blank style='color:#2F92EE;'>#火灾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66889, encryptionId=076b66889cf, topicName=火灾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=46ad14842094, createdName=grace5705, createdTime=Tue Jun 01 08:11:52 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969857, encodeId=015196985e32, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK0iclWFtP7WicKXLyVXAOnRibMria0BwB4otV2d2ibbbkZ2XKAvnNH5x3Y1wm9ibMNZZV5ib5qA0B99sMpw/132, createdBy=9a062530214, createdName=yelinlin, createdTime=Mon May 31 14:27:35 CST 2021, time=2021-05-31, status=1, ipAttribution=)]
    2021-11-04 liuli5079
  3. [GetPortalCommentsPageByObjectIdResponse(id=1885187, encodeId=a2d4188518e9a, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Oct 31 12:11:52 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2088004, encodeId=6a832088004a3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Nov 04 23:11:52 CST 2021, time=2021-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556987, encodeId=2bdd155698ec5, content=<a href='/topic/show?id=076b66889cf' target=_blank style='color:#2F92EE;'>#火灾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66889, encryptionId=076b66889cf, topicName=火灾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=46ad14842094, createdName=grace5705, createdTime=Tue Jun 01 08:11:52 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969857, encodeId=015196985e32, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK0iclWFtP7WicKXLyVXAOnRibMria0BwB4otV2d2ibbbkZ2XKAvnNH5x3Y1wm9ibMNZZV5ib5qA0B99sMpw/132, createdBy=9a062530214, createdName=yelinlin, createdTime=Mon May 31 14:27:35 CST 2021, time=2021-05-31, status=1, ipAttribution=)]
    2021-06-01 grace5705
  4. [GetPortalCommentsPageByObjectIdResponse(id=1885187, encodeId=a2d4188518e9a, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Oct 31 12:11:52 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2088004, encodeId=6a832088004a3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Nov 04 23:11:52 CST 2021, time=2021-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556987, encodeId=2bdd155698ec5, content=<a href='/topic/show?id=076b66889cf' target=_blank style='color:#2F92EE;'>#火灾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66889, encryptionId=076b66889cf, topicName=火灾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=46ad14842094, createdName=grace5705, createdTime=Tue Jun 01 08:11:52 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969857, encodeId=015196985e32, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK0iclWFtP7WicKXLyVXAOnRibMria0BwB4otV2d2ibbbkZ2XKAvnNH5x3Y1wm9ibMNZZV5ib5qA0B99sMpw/132, createdBy=9a062530214, createdName=yelinlin, createdTime=Mon May 31 14:27:35 CST 2021, time=2021-05-31, status=1, ipAttribution=)]
    2021-05-31 yelinlin

    0

相关资讯

NATURE:T细胞是如何介导流产和妊娠期糖尿病的?

胸腺Rank的缺失也会导致Treg细胞在内脏脂肪组织中的积累受损,并与脂肪细胞增大、组织炎症、母体葡萄糖不耐受性增强、胎儿大头症和葡萄糖平衡的长期改变有关,这些都是妊娠期糖尿病的关键标志。

**医学期刊BMJ:42万队列研究,年龄越大,越容易流产;流产次数越多,再次怀孕,流产的风险就越大

流产是妊娠的常见结果,大多数研究表明,妊娠20周后确认的妊娠损失率为12%至15%,量化流产的全部负担具有挑战性,另外,公认损失的总比率对早期妇女识别怀孕的方式很敏感。根据国家登记处或基于人群的队列研究,瑞典,芬兰和丹麦报告的流产风险在12.9%至13.5%之间。虽然大多数流产的原因尚不清楚,但它们可能是由于父母年龄,遗传,激素,免疫和环境因素之间复杂的相互作用造成的。遗传因素,包括父母染色体重排

不同类型流产的超声表现

发生在12周以前的流产定义为早期流产,妊娠12周至不足28周的流产定义为晚期流产。据估计,在人类全部妊娠中,约75%以自然流产告终。

NAT COMMUN:易流产的胚胎发育轨迹有何不同?

人类的生育率非常低。目前认为,非整倍体是人类生殖的主要限制之一,约占早孕损失的50%。此外,非整倍体率在体外受精人类胚胎中是非常高的,根据植入前的非整倍体基因检测(PGT-A).

medRxiv:暨南大学周庆华研究员参与的队列研究,揭示全外显子组测序在妊娠流产中的临床实用性

众所周知,基因异常会导致妊娠丢失。最近的WES研究在84例有超声异常的胎儿死亡病例中分别检测到阳性、可能和候选变异的20%、45%和9%,在19例错失流产的POC病例中,有15例存在序列变异。在一个由

Medicine:流产会增加乳腺癌的发病风险?!NO!

各种流行病学研究表明,流产与无配偶女性患乳腺癌的风险之间存在关联,但结果仍未定论。本荟萃分析在以往研究的基础上对其关联性进行了评估。