JAMA:早产儿胎盘输血与脑室内出血风险

2019-11-20 MedSci MedSci原创

对于孕32周以下的早产儿,接受延迟断脐胎盘输血可降低严重脑室内出血风险

挤压脐带是早产儿胎盘输血的手段之一,近日研究人员考察了早产儿挤压脐带或延迟断脐对死亡率和严重脑室内出血的影响。

妊娠23-31周的早产儿参与研究,随机接受挤压脐带(n=236)或延迟断脐(n=238)。研究的主要结果是合并死亡或严重脑室内出血,非劣性边界1%。

早产儿平均胎龄为28周;女性为46%。挤压脐带组12%(29/236)的患儿死亡或发生严重脑室内出血, 延迟断脐组为8%(20/238,风险差异4%)。尽管在死亡率方面无统计学显著性差异,但是挤压脐带组严重脑室出血率显著高于延迟断脐(8%[20/236]vs3%[8/238];风险差异5%)。在妊娠23-27周的婴儿中,挤压脐带组严重脑室内出血的发生率明显高于延迟断脐(22%[20/93]vs6%[5/89];风险差异16%)。

对于孕32周以下的早产儿,接受延迟断脐胎盘输血可降低严重脑室内出血风险。

原始出处:


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    2019-12-12 yyj062
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    2019-11-22 windight
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    2019-11-22 tastas
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    2019-11-20 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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