旋磨增3倍介入相关心梗风险!北大人民医院刘健等研究

2020-05-18 xunhuan 中国循环杂志

经皮冠状动脉介入相关心肌梗死也称经皮冠状动脉介入后围术期心肌梗死,是经皮冠状动脉介入围术期的严重并发症。

经皮冠状动脉介入相关心肌梗死也称经皮冠状动脉介入后围术期心肌梗死,是经皮冠状动脉介入围术期的严重并发症。

北京大学人民医院刘健等研究提示,年龄、多支病变、支架数目及旋磨均为经皮冠状动脉介入治疗相关心肌梗死发生的独立危险因素,由此建立的危险模型能够较好地指导临床工作者评估经皮冠状动脉介入治疗相关心肌梗死风险。

本研究纳入801例PCI患者,根据心肌梗死全球统一定义,以心肌肌钙蛋白作为经皮冠状动脉介入相关心肌梗死的诊断指标,经皮冠状动脉介入相关心肌梗死发生率为14.1%(113/801)。

相比于无经皮冠状动脉介入相关心肌梗死组,经皮冠状动脉介入相关心肌梗死组男性比例更低,年龄更高,体重指数更低,入院时出现心力衰竭比例更高。

在冠状动脉造影及经皮冠状动脉介入治疗方面,经皮冠状动脉介入相关心肌梗死组多支病变、多支干预、靶病变存在钙化、靶病变进行旋磨治疗等的比例均更高,置入支架也更多。

研究者利用Logistic回归分析筛选出了经皮冠状动脉介入相关心肌梗死发生的独立危险因素:年龄、多支病变、支架数目及旋磨。

基于四个因素,研究者建立了经皮冠状动脉介入相关心肌梗死的危险模型,该模型的ROC 曲线下面积为0.706。

来源:周沛, 赵宇彤,巩师毅,等. 经皮冠状动脉介入治疗相关心肌梗死的危险因素和预测模型的建立. 中国循环杂志,2020,35:450-454.

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    2020-09-14 辣妈

    学习了

    0

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