Neuroradiology:RANO标准、对比增强和灌注MRI在评估胶质母细胞瘤进展的价值。

2017-09-19 shaosai MedSci原创

多形性胶质母细胞瘤简称为胶母细胞瘤,按Kernohan分类属星形细胞瘤3~4级。胶质母细胞瘤是最常见的脑胶质瘤之一,占胶质瘤的25%以上,也是最恶性的一种。男性多于女性,男女之比约为3:1。大多发生于成人,特别是30~50岁间。胶质母细胞瘤呈浸润性生长,病程迅速进展,手术切除后常很快复发。本研究旨在评价多形性胶质母细胞瘤(GBM)神经肿瘤反应评价标准关于Macdonald标准和对比增强(CE)体积

多形性胶质母细胞瘤简称为胶母细胞瘤,按Kernohan分类属星形细胞瘤3~4级。胶质母细胞瘤是最常见的脑胶质瘤之一,占胶质瘤的25%以上,也是最恶性的一种。男性多于女性,男女之比约为3:1。大多发生于成人,特别是30~50岁间。胶质母细胞瘤呈浸润性生长,病程迅速进展,手术切除后常很快复发。本研究旨在评价多形性胶质母细胞瘤(GBM)神经肿瘤反应评价标准关于Macdonald标准和对比增强(CE)体积变化的关系。并探究相对脑血流量(rCBV)的相对变化,并将结果发表在Neuroradiology上。本研究共纳入了自2006-2010年的43例患者,所有患者进行了手术切除,并行术后基于替莫唑胺的放化疗。回顾性分析MR图像。根据RANO标准的进展时间(TTPs),对比Macdonald标准和CE体积增加(CE-3D)间的差异,并评价rCBV第75%分位数(rCBV75)的百分比变化。在随访中位时间22.7个月之后,参照RANO标准、CE-3D和Macdonald标准,分别共有39、32、42例患者病变发生进展。中位TTPs分别为6.4、9.3和6.6个月。在RANO和CE-3D、RANO和Ma

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    2017-09-19 shaosai

    好好学习.谢谢分享!

    0

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    2017-09-19 清风拂面

    学习了.谢谢分享

    0

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    2017-09-19 Y—xianghai

    学习了新知识

    0

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    2017-09-19 圣艮山

    学习了不少事情!

    0

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