J INTERN MED:坚持摄入蔬菜可降低非酒精性脂肪肝患者的2型糖尿病风险

2021-12-08 MedSci原创 MedSci原创

非酒精性脂肪肝是中国人群发生2型糖尿病的重要危险因素。值得注意的是,坚持摄入蔬菜的饮食模式可以降低这种风险,对于体瘦的非酒精性脂肪肝患者尤其如此。

非酒精性脂肪肝是2型糖尿病的重要危险因素。然而,没有研究调查饮食摄入是否可以改变非酒精性脂肪肝的这种效应。

近日,内科学领域权威杂志Journal of Internal Medicine上发表一篇研究文章,研究人员旨在探究饮食模式改变对非酒精性脂肪肝与2型糖尿病之间关联的影响。

该研究是一项在中国进行了大型前瞻性队列研究(n=24602)。考虑到饮酒,研究人员使用肝脏超声检查诊断非酒精性脂肪肝情况。研究人员使用经过验证的自我管理食物频率问卷评估受试者的饮食数据。Cox比例风险回归用于估计非酒精性脂肪肝与2型糖尿病之间关联的风险比(HR)和95%置信区间(CI)。

经过93873人次每年的随访,787名(3.20%)参与者发展为2型糖尿病。在多变量调整模型中,与未患非酒精性脂肪肝的参与者相比,非酒精性脂肪肝患者发生2型糖尿病的HR(95%CI)为3.04(2.51-3.68)。在亚组分析中,较低(≤中位数)和较高(>中位数)蔬菜摄入量的非酒精性脂肪肝患者发生2型糖尿病的调整后HR(95%CI)分别为4.08(3.05-5.46)和2.38(1.85-3.07))(交互作用的P<0.01)。此外,研究人员发现较高的蔬菜摄入量可以减弱非酒精性脂肪肝对2型糖尿病风险的影响,在体瘦的非酒精性脂肪肝患者中尤其如此。

由此可见,非酒精性脂肪肝是中国人群发生2型糖尿病的重要危险因素。值得注意的是,坚持摄入蔬菜的饮食模式可以降低这种风险,对于体瘦的非酒精性脂肪肝患者尤其如此。

原始出处:

Yang Xia,et al.Adherence to a vegetable dietary pattern attenuates the risk of non-alcoholic fatty liver disease on incident type 2 diabetes: the TCLSIH cohort study.Journal of Internal Medicine.2021.https://onlinelibrary.wiley.com/doi/10.1111/joim.13428

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    2022-02-03 胡国宏
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    2021-12-10 zhaojie88
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    2021-12-09 419040982

    吃什么菜,种类???

    0

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