BJU Int:根治性前列腺切除术后,哪些患者需要进行尿失禁手术干预?

2021-12-29 AlexYang MedSci原创

调查了前列腺根治术后患者报告的尿失禁和困扰评分是否会导致随后的尿失禁手术干预。

患者报告的结果(PROs)可用于评估前列腺癌治疗对患者症状、功能结果和生活质量的影响。现代临床试验使用PROs进行更全面的结果评估,其中包括副作用。

近期,来自美国的研究人员在《BJU Int》上发表文章,调查了前列腺根治术后患者报告的尿失禁和困扰评分是否会导致随后的尿失禁手术干预

研究人员鉴定了2014年4月-2016年1月期间在英国国家卫生服务机构诊断为前列腺癌的男性。使用管理性数据确定了接受根治性前列腺切除术的男性以及随后接受尿失禁手术的男性。国家前列腺癌审计数据库用来确定那些完成了治疗后调查的男性。调查包括扩展的前列腺癌综合指数(EPIC-26)。根据EPIC-26的尿失禁评分,探讨了调查后6个月内行尿失禁手术的频率,还探讨了EPIC-26尿失禁得分 "良好"(≥75分)或 "糟糕"(≤25分)与排尿困扰的看法之间的关系(对其排尿功能的回答从 "无问题 "到 "大问题 "不等)。

研究最终纳入了11290名接受过前列腺根治术的男性。尿失禁手术的3年累积发生率为2.5%。经过筛选,研究人员确定有5165名男性在中位时间19个月后完成了治疗后调查(回复率74%)。其中,481名男性(9.3%)报告尿失禁评分为 "糟糕",207名男性(4.0%)报告他们的排尿功能有很大问题。47名男性在调查完成后的6个月内进行尿失禁手术(0.9%),其中93.6%的男性尿失禁评分为 "糟糕"。在尿失禁评分最差(0分)的71名男性中,只有11名男性(15.5%)随后进行了尿失禁手术。

不同尿失禁评分下,患者报告的泌尿困扰结果情况

 

综上所述,有大量的男性在前列腺根治术后患有严重的、令人困扰的尿失禁,并且尿失禁手术的临床需求没有得到满足。因此,系统收集患者报告的结果可用于识别那些可能从尿失禁手术中受益的男性

 

原始出处:

Matthew G Parry , Ted A Skolarus , Julie Nossiter et al. Urinary incontinence and use of incontinence surgery after radical prostatectomy: a national study using patient-reported outcomes. BJU Int. 2021

 

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createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2022-05-14 jiaqilei

    学习了

    0

  3. 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createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2022-03-19 疏通下水道

    所以现在才回不断地探索改善PPI的技术

    0

  4. 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GetPortalCommentsPageByObjectIdResponse(id=1191320, encodeId=bfb411913209c, content=涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=57de6415950, createdName=ms5000000254917531, createdTime=Wed Feb 09 08:14:10 CST 2022, time=2022-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708897, encodeId=f9fc1e08897d2, content=<a href='/topic/show?id=ffca32501e6' target=_blank style='color:#2F92EE;'>#前列腺切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32501, encryptionId=ffca32501e6, topicName=前列腺切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cbe731571573, createdName=1249898am25暂无昵称, createdTime=Mon Oct 03 08:28:55 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085520, encodeId=982910855209e, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>前列腺治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:15:33 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085506, encodeId=c15c1085506a4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:09:15 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281692, encodeId=6f9f128169276, content=<a href='/topic/show?id=0c3c4e407ec' target=_blank style='color:#2F92EE;'>#尿失禁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47407, encryptionId=0c3c4e407ec, topicName=尿失禁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586274, encodeId=a28f15862e47b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2041496, encodeId=743a204149671, content=<a href='/topic/show?id=7d30544167c' target=_blank style='color:#2F92EE;'>#手术干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54416, encryptionId=7d30544167c, topicName=手术干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Mon Oct 24 12:28:55 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219567, encodeId=f312121956e10, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=395f2314684, createdName=jiaqilei, createdTime=Sat May 14 13:55:14 CST 2022, time=2022-05-14, status=1, ipAttribution=), 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GetPortalCommentsPageByObjectIdResponse(id=1085520, encodeId=982910855209e, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>前列腺治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:15:33 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085506, encodeId=c15c1085506a4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:09:15 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281692, encodeId=6f9f128169276, content=<a href='/topic/show?id=0c3c4e407ec' target=_blank style='color:#2F92EE;'>#尿失禁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47407, encryptionId=0c3c4e407ec, topicName=尿失禁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586274, encodeId=a28f15862e47b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2022-02-09 ms5000000254917531

    涨知识

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2041496, encodeId=743a204149671, content=<a href='/topic/show?id=7d30544167c' target=_blank style='color:#2F92EE;'>#手术干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54416, encryptionId=7d30544167c, topicName=手术干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Mon Oct 24 12:28:55 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219567, encodeId=f312121956e10, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=395f2314684, createdName=jiaqilei, createdTime=Sat May 14 13:55:14 CST 2022, time=2022-05-14, status=1, ipAttribution=), 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GetPortalCommentsPageByObjectIdResponse(id=1085520, encodeId=982910855209e, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>前列腺治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:15:33 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085506, encodeId=c15c1085506a4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:09:15 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281692, encodeId=6f9f128169276, content=<a href='/topic/show?id=0c3c4e407ec' target=_blank style='color:#2F92EE;'>#尿失禁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47407, encryptionId=0c3c4e407ec, topicName=尿失禁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586274, encodeId=a28f15862e47b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2041496, encodeId=743a204149671, content=<a href='/topic/show?id=7d30544167c' target=_blank style='color:#2F92EE;'>#手术干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54416, encryptionId=7d30544167c, topicName=手术干预)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Mon Oct 24 12:28:55 CST 2022, time=2022-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1219567, encodeId=f312121956e10, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=395f2314684, createdName=jiaqilei, createdTime=Sat May 14 13:55:14 CST 2022, time=2022-05-14, status=1, ipAttribution=), 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GetPortalCommentsPageByObjectIdResponse(id=1085520, encodeId=982910855209e, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>前列腺治疗, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:15:33 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085506, encodeId=c15c1085506a4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d25a5516768, createdName=一己怀, createdTime=Wed Dec 29 17:09:15 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281692, encodeId=6f9f128169276, content=<a href='/topic/show?id=0c3c4e407ec' target=_blank style='color:#2F92EE;'>#尿失禁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47407, encryptionId=0c3c4e407ec, topicName=尿失禁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586274, encodeId=a28f15862e47b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2021-12-29 一己怀

    #学习#前列腺治疗

    0

  8. 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GetPortalCommentsPageByObjectIdResponse(id=1281692, encodeId=6f9f128169276, content=<a href='/topic/show?id=0c3c4e407ec' target=_blank style='color:#2F92EE;'>#尿失禁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47407, encryptionId=0c3c4e407ec, topicName=尿失禁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586274, encodeId=a28f15862e47b, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2021-12-29 一己怀

    学习了

    0

  9. 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  10. 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createdName=jeanqiuqiu, createdTime=Wed Dec 29 11:28:55 CST 2021, time=2021-12-29, status=1, ipAttribution=)]
    2021-12-29 jeanqiuqiu

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