Prostate Cancer P D:根治性前列腺切除患者术前体弱能够预测短期术后不良结果

2020-03-30 AlexYang MedSci原创

最近,有研究人员在根治性前列腺切除(RP)治疗的前列腺癌患者中调查了体弱对短期术后结果的影响。

最近,有研究人员在根治性前列腺切除(RP)治疗的前列腺癌患者中调查了体弱对短期术后结果的影响。

在国家住院样本数据库中,研究人员鉴定了91618名在2008年和2015年之间治疗的RP患者。总的来讲,共有12185(13.3%)名患者为体弱。研究发现,体弱患者的比例随着时间而增加(从10.3%到18.2%;p<0.001),且他们具有更高的总体并发症比例(16.6% vs. 8.6%),主要并发症比例(4.9 vs. 2.6%)和非家居出院(5.9% vs. 5%)比例,以及更长的住院时间(LOS)和更高的总住院费用(THCs)($37186 vs. $35241)(所有p<0.001)。更多的是,体弱是总并发症(OR:1.95)、主要并发症(OR:1.76)、非家居出院(OR:1.20)、更长的LOS(RR:1.19)和更高的THCs(RR: $3160)的独立预测因子(所有p<0.001)。在体弱患者中,10418(85.5%)名患者的身体质量指数既没有≥30,也没有查尔森并存症指数≥2。

最后,研究人员指出,平均来讲有七分之一的患者为体弱,并且该比例在增加。体弱个体的短期不良术后结果风险更高,并且不能通过其他风险因子进行预测,比如肥胖或者并存病。

原始出处:

Giuseppe Rosiello, Carlotta Palumbo, Sophie Knipper et al. Preoperative frailty predicts adverse short-term postoperative outcomes in patients treated with radical prostatectomy. Prostate Cancer P D. 18 Mar 2020

 

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    2020-04-01 lsndxfj
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    2020-04-01 jeanqiuqiu
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    2020-04-01 sunylz

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