JAHA:体重指数和腰围与房颤之间的相关性

2021-04-15 MedSci原创 MedSci原创

男性和女性参与者BMI(大于20 kg/m2)与AF以及WC与AF之间呈正相关。BMI似乎是关于女性AF风险更有用的量度指标,而WC似乎是对男性更有价值的指标。

肥胖与房颤之间的相关性可能因性别而异。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在通过体重指数(BMI)和腰围(WC)来精准估计男性和女性发生房颤的风险。

在2008年至2013年期间,超过320万成年人进入商业​​性筛查诊所。参与者完成了健康调查表,并进行了体格检查以及包括心电图在内的心血管检查。研究人员排除了患有心血管疾病的患者。研究人员使用多变量logistic回归进行分析,并通过比较似然比χ2统计量确定了BMI和WC与男女性患者房颤风险的联合相关性。

在210万参与者中,有12067(0.6%)患者发生房颤。在BMI大于20 kg/m2的参与者中,BMI每增加5 kg/m2与AF呈正相关,男性比值比为1.65(95%CI为1.57–1.73),女性为1.36(95%CI为1,30–1.42)。

研究人员发现,AF和WC呈正相关,其每增加10 cm,男性参与者比值比为1.47(95%CI为1.36-1.60),女性比值比为1.37(95%CI为1.26-1.49)。将BMI和WC添加到所有参与者的模型中后,似然比χ2的改善程度相当。在男性中,WC的似然比χ2的改善程度比BMI强(30% vs. 23%)。在女性中,BMI的似然比χ2的改善程度比WC强(23% vs. 12%)。

由此可见,男性和女性参与者BMI(大于20 kg/m2)与AF以及WC与AF之间呈正相关。BMI似乎是关于女性AF风险更有用的量度指标,而WC似乎是对男性更有价值的指标。

原始出处:

Michiel H. F. Poorthuis.et al.Joint Associations Between Body Mass Index and Waist Circumference With Atrial Fibrillation in Men and Women.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.019025

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1837925, encodeId=2d70183e92518, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Mon Jan 24 23:44:11 CST 2022, time=2022-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=963344, encodeId=2c159633442a, content=谢谢学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/05/22/c26524b0b4ca80000d38f0294262c002.jpg, createdBy=3cf52015303, createdName=苏小雨, createdTime=Fri May 07 10:48:38 CST 2021, time=2021-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958264, encodeId=30679582649f, content=肥胖就是不好啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ZJYYY7, createdTime=Mon Apr 19 11:31:00 CST 2021, time=2021-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268492, encodeId=dbce1268492e3, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Apr 17 12:44:11 CST 2021, time=2021-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308148, encodeId=7ab5130814888, content=<a href='/topic/show?id=8f0085426a7' target=_blank style='color:#2F92EE;'>#腰围#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85426, encryptionId=8f0085426a7, topicName=腰围)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b0e350, createdName=naiwu77, createdTime=Sat Apr 17 12:44:11 CST 2021, time=2021-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=957605, encodeId=504595e60583, content=肥胖与房颤之间的相关性可能因性别而异, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Fri Apr 16 15:28:06 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031373, encodeId=b15e10313e312, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Fri Apr 16 00:44:11 CST 2021, time=2021-04-16, status=1, ipAttribution=)]
    2021-05-07 苏小雨

    谢谢学习了

    0

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    2021-04-19 ZJYYY7

    肥胖就是不好啊

    0

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    2021-04-17 zhaohui6731
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    2021-04-17 naiwu77
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    2021-04-16 言西早

    肥胖与房颤之间的相关性可能因性别而异

    0

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    2021-04-16 心介

    房颤,临床上碰到很多哦

    0

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