Otolaryngol Head Neck Surg:年龄相关的中央听觉处理器障碍、MCI和痴呆研究

2020-05-07 AlexYang MedSci原创

最近,有研究人员在一个老年群体中探索了年龄相关的中央听觉处理器障碍(CAPD)与轻度认知损伤(MCI)和痴呆之间的相关性。

最近,有研究人员在一个老年群体中探索了年龄相关的中央听觉处理器障碍(CAPD)与轻度认知损伤(MCI)和痴呆之间的相关性。

研究是一个代表性的基于群体的研究。在2013年和2018年之间,研究人员对1647名>65岁的健康志愿者进行了MCI、痴呆、年龄相关的CAPD(无残基听力损失,SSI-ICM测试评分<50%)、神经学和神经心理学检查以及血清代谢生物标记物检测等调查。研究发现,年龄相关CAPD、MCI和痴呆的发生率分别为14.15%、15.79%和3.58%。在具有MCI和痴呆的受试者中,19.61%和42.37%的受试者具有年龄相关的CAPD。在回归模型分析中,年龄相关的CAPD与MCI(OR,1.50; 95% CI, 1.01-2.21)和痴呆(OR,2.23; 95% CI, 1.12-4.42)相关。在线性模型中,整体认知评分与SSI-ICM评分的增加呈现正相关关系。所有的模型均依据人口统计学和代谢性血清生物标志物进行了调整。

最后,研究人员指出,年龄相关的CAPD与MCI和痴呆的紧密相关性表明了神经退化中中央听觉处理器的参与,但是联系的方向未知。但CAPD是老年患者认知障碍中的一个可能的诊断标记。

原始出处:

Sardone R, Battista P, Donghia R et al. Age-Related Central Auditory Processing Disorder, MCI, and Dementia in an Older Population of Southern Italy. Otolaryngol Head Neck Surg. 21 April 2020.

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1933482, encodeId=bef619334829c, content=<a href='/topic/show?id=79654901349' target=_blank style='color:#2F92EE;'>#年龄相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49013, encryptionId=79654901349, topicName=年龄相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8143398, createdName=lily1616, createdTime=Sun Dec 27 07:28:05 CST 2020, time=2020-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044132, encodeId=d9d12044132a1, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Wed Oct 07 22:28:05 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519385, encodeId=374e1519385ac, content=<a href='/topic/show?id=3731113e8c3' target=_blank style='color:#2F92EE;'>#MCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11378, encryptionId=3731113e8c3, topicName=MCI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=934111256894, createdName=hukaixun, createdTime=Sat May 09 05:28:05 CST 2020, time=2020-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048619, encodeId=77061048619e4, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu May 07 17:28:05 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1933482, encodeId=bef619334829c, content=<a href='/topic/show?id=79654901349' target=_blank style='color:#2F92EE;'>#年龄相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49013, encryptionId=79654901349, topicName=年龄相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8143398, createdName=lily1616, createdTime=Sun Dec 27 07:28:05 CST 2020, time=2020-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044132, encodeId=d9d12044132a1, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Wed Oct 07 22:28:05 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519385, encodeId=374e1519385ac, content=<a href='/topic/show?id=3731113e8c3' target=_blank style='color:#2F92EE;'>#MCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11378, encryptionId=3731113e8c3, topicName=MCI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=934111256894, createdName=hukaixun, createdTime=Sat May 09 05:28:05 CST 2020, time=2020-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048619, encodeId=77061048619e4, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu May 07 17:28:05 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1933482, encodeId=bef619334829c, content=<a href='/topic/show?id=79654901349' target=_blank style='color:#2F92EE;'>#年龄相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49013, encryptionId=79654901349, topicName=年龄相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8143398, createdName=lily1616, createdTime=Sun Dec 27 07:28:05 CST 2020, time=2020-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044132, encodeId=d9d12044132a1, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Wed Oct 07 22:28:05 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519385, encodeId=374e1519385ac, content=<a href='/topic/show?id=3731113e8c3' target=_blank style='color:#2F92EE;'>#MCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11378, encryptionId=3731113e8c3, topicName=MCI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=934111256894, createdName=hukaixun, createdTime=Sat May 09 05:28:05 CST 2020, time=2020-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048619, encodeId=77061048619e4, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu May 07 17:28:05 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-05-09 hukaixun
  4. [GetPortalCommentsPageByObjectIdResponse(id=1933482, encodeId=bef619334829c, content=<a href='/topic/show?id=79654901349' target=_blank style='color:#2F92EE;'>#年龄相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49013, encryptionId=79654901349, topicName=年龄相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8143398, createdName=lily1616, createdTime=Sun Dec 27 07:28:05 CST 2020, time=2020-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044132, encodeId=d9d12044132a1, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Wed Oct 07 22:28:05 CST 2020, time=2020-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519385, encodeId=374e1519385ac, content=<a href='/topic/show?id=3731113e8c3' target=_blank style='color:#2F92EE;'>#MCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11378, encryptionId=3731113e8c3, topicName=MCI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=934111256894, createdName=hukaixun, createdTime=Sat May 09 05:28:05 CST 2020, time=2020-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1048619, encodeId=77061048619e4, content=老年人痴呆何药可用??, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=junJUN, createdTime=Thu May 07 17:28:05 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-05-07 junJUN

    老年人痴呆何药可用??

    0

相关资讯

Age aging:运动少、高血压和低学历是我国痴呆三大原因!中国25万人分析

近期,一项研究提示,运动少、高血压和低学历是我国老年痴呆的三大原因。

Neurology:阿司匹林对痴呆和认知能力下降的影响

没有证据表明阿司匹林能有效降低痴呆、MCI或认知能力下降的风险。

患者病情好转后出院,1周时间就痴呆了,为啥?

脑白质病变的患者出院后痴呆了,究竟为何?又该如何诊断治疗?先看看病例:

盘点:脑小血管病相关研究汇总

脑小血管病相关汇总

JAMA Neurol:心血管疾病、大气污染与痴呆风险

研究发现,长期暴露在空气污染下,患痴呆症的风险更高。心力衰竭和缺血性心脏病似乎增强了空气污染与痴呆之间的联系,而中风似乎是空气污染暴露与痴呆风险之间的重要中间条件

J Neurol Neurosur Ps:血清同型半胱氨酸与痴呆风险

血清高tHcy水平与痴呆、AD和VaD风险增高呈非线性关系,仅在tHcy水平相对高的范围内存在剂量-反应相关性。