Am J Resp Crit Care:学龄儿童哮喘对肥胖有影响吗?

2017-01-22 xing.T MedSci原创

患有哮喘的儿童发生肥胖的风险较高。哮喘救援药物的使用可以独立的体力活动来减少肥胖的发生风险。

哮喘和肥胖经常在儿童中一起发生,然而目前还不清楚哮喘是否会导致儿童肥胖症的流行。近日,呼吸内科领域权威杂志Am J Resp Crit Care上发表了一篇研究文章,研究人员旨在调查哮喘和哮喘药物治疗对儿童发生肥胖的影响。

研究人员对从南加利福尼亚儿童健康研究(CHS研究)中招募的2171名5-8岁的非肥胖儿童进行主要分析,并且对这些研究对象进行了为期10年的随访。另外,研究人员对来自CHS研究中的2684名儿童组成的独立样本进行重复分析,并对其从9.7岁随访到17.8岁。

研究人员每年测量这些研究儿童的身高和体重,并据此将儿童分为正常、超重和肥胖等组别。哮喘状况是指由父母或自我报告的并经医生诊断哮喘。研究人员采用Cox比例风险模型进行拟合来评估在研究随访期间哮喘病史与肥胖发生率之间的相关性。

调整混杂因素后,研究人员发现在分组之时被诊断为哮喘并分入哮喘组的患儿相比于未被诊断为哮喘的儿童在儿童和青少年时期发生肥胖的风险要增加51%[风险比和95%可信区间为1.51(1.08-2.10]。在研究分组之时使用哮喘救援药物可以降低发生肥胖的风险[风险比和95%可信区间为0.57(0.33-0.96)]。此外,哮喘病史和发生肥胖风险增加之间的显著相关性在独立的社区样本中也可以重复出来。

由此可见,患有哮喘的儿童发生肥胖的风险较高。哮喘救援药物的使用可以独立的体力活动来减少肥胖的发生风险。

原始出处:

Zhanghua Chen , et al. Effects of Childhood Asthma on the Development of Obesity among School-aged Children. AM J RESP CRIT CARE 2017. http://www.atsjournals.org/doi/abs/10.1164/rccm.201608-1691OC

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    2017-02-07 幸运8355

    观点非常好,学习了

    0

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    2017-01-25 186****0580(小山羊)

    学习了,知道了!

    0

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    2017-01-23 knowheart

    很好的学习资料收藏

    0

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    2017-01-23 1dd8aa01m06(暂无匿称)

    好文章,学习了

    0

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    2017-01-22 tanxingdoctor

    学习了,很不错

    0

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    2017-01-22 蓝莓花青素

    了解了,非常不错?

    0

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