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Galderma：新数据显示口服和局部联合治疗严重丘疹脓疱性红斑痤疮患者的临床益处

2019-03-02 不详 MedSci原创

丘疹脓疱性红斑痤疮强力霉素伊维菌素
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Galderma分享了其ANSWER研究的结果，该研究强调了与伊维菌素1％乳膏（IVM）加安慰剂组合相比，使用强力霉素40 mg改良释放胶囊（DMR）和IVM联合治疗严重丘疹脓疱性红斑痤疮患者的炎症性病变临床益处。根据结果显示，与IVM加安慰剂相比，联合治疗与在12周时达到100％病变清除率的患者比例增加了2.5倍（17.8％对7.2％）。DMR和IVM的作用也明显快于IVM加安慰剂，早在第4周就

Galderma分享了其ANSWER研究的结果，该研究强调了与伊维菌素1％乳膏（IVM）加安慰剂组合相比，使用强力霉素40 mg改良释放胶囊（DMR）和IVM联合治疗严重丘疹脓疱性红斑痤疮患者的炎症性病变临床益处。

根据结果显示，与IVM加安慰剂相比，联合治疗与在12周时达到100％病变清除率的患者比例增加了2.5倍（17.8％对7.2％）。DMR和IVM的作用也明显快于IVM加安慰剂，早在第4周就可以看到显着差异。两个治疗组的安全性耐受良好，两组之间无显着差异。

该数据在美国华盛顿特区2019年美国皮肤病学会（AAD）年会的一张海报透露。

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    2019-03-04 zhaozuguo

    #联合治疗#

    0

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    2019-03-04 chg122

    #局部#

    0

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    2019-03-04 zhouqu_8

    #红斑#

    0

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    2019-03-04 zhangjingnwpu

    #ALD#

    0

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    2019-03-04 ms7517674339485982

    #丘疹#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1313736, encodeId=1cc51313e36c1, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405893, encodeId=069c140589371, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436204, encodeId=8c7b14362049e, content=<a href='/topic/show?id=22f8e71238d' target=_blank style='color:#2F92EE;'>#红斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77123, encryptionId=22f8e71238d, topicName=红斑)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469406, encodeId=126b146940664, content=<a href='/topic/show?id=9d6522e613' target=_blank style='color:#2F92EE;'>#ALD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2276, encryptionId=9d6522e613, topicName=ALD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64f67025397, createdName=zhangjingnwpu, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1480742, encodeId=e19d1480e4230, content=<a href='/topic/show?id=0bc3208e417' target=_blank style='color:#2F92EE;'>#丘疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20874, encryptionId=0bc3208e417, topicName=丘疹)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=26147676061, createdName=ms7517674339485982, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587546, encodeId=1049158e54628, content=<a href='/topic/show?id=a44322e85d' target=_blank style='color:#2F92EE;'>#Alder#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2278, encryptionId=a44322e85d, topicName=Alder)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e79417492785, createdName=xuqianhua, createdTime=Mon Mar 04 01:52:00 CST 2019, time=2019-03-04, status=1, ipAttribution=)]
    2019-03-04 xuqianhua

    #Alder#

    0