Am J Clin Nutr:枸杞可以增强健康饮食方式对心血管的保护作用

2021-05-10 MedSci原创 MedSci原创

枸杞作为一种健康食品在亚洲有着悠久的食用历史,在动物和体外研究中,枸杞显示出降血脂,抗氧化和抗炎的特性,有研究显示。

      枸杞作为一种健康食品在亚洲有着悠久的食用历史,在动物和体外研究中,枸杞显示出降血脂,抗氧化和抗炎的特性,有研究显示。在临床上在经过45天的干预后,每天摄入14g枸杞,可以显著改善患有代谢综合征的个体的血脂-脂蛋白谱。但是目前还没有文章对食用枸杞是否可以降低血管疾病(CVD)风险进行研究,因此,本项研究旨在对食用枸杞对老年人的血管健康相关结局和经典CVD危险因素的影响进行相关评估。

 

      这是一个为期16周的随机对照试验。所有参与者(n  = 40)均接受了饮食咨询,以遵循健康饮食习惯的建议,枸杞组给予了额外的指导,以做饭和食用15 g/d的全干枸杞干作为主要膳食。对患者的血管功能(血流介导的扩张,血浆总硝酸盐/亚硝酸盐,内皮素-1和细胞间粘附分子-1),血管结构(颈动脉内膜中层厚度)和血管再生情况(内皮祖细胞计数,血浆血管生成素1和在基线和干预后评估血管生成素2)进行了检测。同时每4周评估一次血清脂质脂蛋白和血压变化。

 

      研究结果显示所有参与者的健康饮食习惯的依从性均得到改善。食用枸杞与总硝酸盐/亚硝酸盐浓度的显着升高相关(枸杞:3.92±1.73 nmol/mL VS 5.01±2.55 nmol/L),同时内皮素-1浓度的明显降低(枸杞:-0.19±0.06 pg / mL VS -0.15±0.08pg/mL)。与对照组相比,枸杞组的HDL胆固醇(0.08±0.04 mmol/L)明显高于基线,而长期CVD风险较低(-0.8±0.5%)。

图:枸杞可以减少促炎细胞的增殖

      本项研究证实在中老年人中,坚持健康的饮食习惯可改善血管紧张度。在饮食中加入枸杞可进一步改善血脂-脂蛋白谱,并可能降低长期CVD的发生风险。

 

原始出处 :

Darel Wee Kiat Toh. Et al. Enhancing the cardiovascular protective effects of a healthy dietary pattern with wolfberry (Lycium barbarum): A randomized controlled trial. The American Journal of Clinical Nutrition.2021.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=2007294, encodeId=a95e200e294cd, content=<a href='/topic/show?id=e5c5101241e7' target=_blank style='color:#2F92EE;'>#饮食方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101241, encryptionId=e5c5101241e7, topicName=饮食方式)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Oct 12 08:45:38 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599158, encodeId=3b521599158ef, content=<a href='/topic/show?id=f14d2e187ac' target=_blank style='color:#2F92EE;'>#保护作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27187, encryptionId=f14d2e187ac, topicName=保护作用)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2ee918684940, createdName=photoman, createdTime=Wed May 12 00:45:38 CST 2021, time=2021-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=964656, encodeId=6810964656ac, content=一天15g,是不是量有点多,会上火把, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/c8abcfae504447d79198f8be33572229/accf6d2da0ee4425954ba2cbd65ce5ec.jpg, createdBy=38281876637, createdName=ms9457755563275660, createdTime=Tue May 11 17:47:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=964655, encodeId=e38a96465504, content=没看懂啥意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/c8abcfae504447d79198f8be33572229/accf6d2da0ee4425954ba2cbd65ce5ec.jpg, createdBy=38281876637, createdName=ms9457755563275660, createdTime=Tue May 11 17:47:02 CST 2021, time=2021-05-11, status=1, ipAttribution=)]
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    2021-05-11 ms9457755563275660

    一天15g,是不是量有点多,会上火把

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2007294, encodeId=a95e200e294cd, content=<a href='/topic/show?id=e5c5101241e7' target=_blank style='color:#2F92EE;'>#饮食方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101241, encryptionId=e5c5101241e7, topicName=饮食方式)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Oct 12 08:45:38 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599158, encodeId=3b521599158ef, content=<a href='/topic/show?id=f14d2e187ac' target=_blank style='color:#2F92EE;'>#保护作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27187, encryptionId=f14d2e187ac, topicName=保护作用)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2ee918684940, createdName=photoman, createdTime=Wed May 12 00:45:38 CST 2021, time=2021-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=964656, encodeId=6810964656ac, content=一天15g,是不是量有点多,会上火把, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/c8abcfae504447d79198f8be33572229/accf6d2da0ee4425954ba2cbd65ce5ec.jpg, createdBy=38281876637, createdName=ms9457755563275660, createdTime=Tue May 11 17:47:34 CST 2021, time=2021-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=964655, encodeId=e38a96465504, content=没看懂啥意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210511/c8abcfae504447d79198f8be33572229/accf6d2da0ee4425954ba2cbd65ce5ec.jpg, createdBy=38281876637, createdName=ms9457755563275660, createdTime=Tue May 11 17:47:02 CST 2021, time=2021-05-11, status=1, ipAttribution=)]
    2021-05-11 ms9457755563275660

    没看懂啥意思

    0

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