JAHA:中心性肥胖和内脏脂肪组织与老年男性心血管事件无关

2018-08-20 xing.T MedSci原创

由此可见,通过VAT或android-gynoid脂肪比率衡量的中心脂肪组织与老年男性的ASCVD事件无关。

内脏脂肪组织(VAT)和其他中心性肥胖指标可预测中年人发生的动脉粥样硬化性血管疾病(ASCVD)事件,但这些关联在70岁及以上的老年人中尚未明确。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在评估老年男性VAT和另一项中心性肥胖衡量指标android/gynoid脂肪比率与ASCVD事件之间的关联。

研究人员对参与“老年男性睡眠障碍结局”研究的2899名男性(平均[SD]年龄为76.3[5.5]岁)的ASCVD事件(心肌梗塞、冠心病死亡、致命性或非致命性卒中)进行了严格裁决。研究人员使用比例风险模型来估计VAT和android/gynoid脂肪比率(在基线时用双能量吸光光度法进行测量)每增加1个SD发生ASCVD事件的风险比,并且调整了年龄、种族、受教育程度、收缩压、吸烟状况、氧化低密度脂蛋白水平、降压治疗、他汀类药物使用、阿司匹林使用、糖尿病和研究登记网点。

在7.9(3.4)年的平均(SD)随访期内,424名(14.6%)男性参与者发生了ASCVD事件。无论是未调整还是多变量调整后,VAT和android/gynoid脂肪比率均与ASCVD事件的发生无关(每SD增加的风险比[95%置信区间]分别为1.02 [0.92-1.13]和1.05 [0.95-1.17])。

由此可见,通过VAT或android-gynoid脂肪比率衡量的中心脂肪组织与老年男性的ASCVD事件无关。

原始出处:

John T. Schousboe.et al. Central Obesity and Visceral Adipose Tissue Are Not Associated With Incident Atherosclerotic Cardiovascular Disease Events in Older Men.JAHA.2018. https://www.ahajournals.org/doi/full/10.1161/JAHA.118.009172

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    2018-08-27 huangshang9812

    哈哈哈,学习了

    0

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    2018-08-22 zhaohui6731
  6. [GetPortalCommentsPageByObjectIdResponse(id=1897809, encodeId=c0da189e80921, content=<a href='/topic/show?id=a3b080193fe' target=_blank style='color:#2F92EE;'>#老年男性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80193, encryptionId=a3b080193fe, topicName=老年男性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Sat Feb 23 02:05:00 CST 2019, time=2019-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976755, encodeId=39bd19e6755cb, content=<a href='/topic/show?id=09543050860' target=_blank style='color:#2F92EE;'>#内脏脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30508, encryptionId=09543050860, topicName=内脏脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, createdName=crystal0562, createdTime=Wed Dec 19 15:05:00 CST 2018, time=2018-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643561, encodeId=345c1643561a3, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Apr 12 12:05:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341149, encodeId=73ed34114986, content=哈哈哈,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e1ee1608797, createdName=huangshang9812, createdTime=Mon Aug 27 14:21:35 CST 2018, time=2018-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267896, encodeId=7914126e896bb, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Wed Aug 22 13:05:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345772, encodeId=8a161345e7222, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Wed Aug 22 13:05:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340037, encodeId=d31634003e20, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Aug 21 23:35:25 CST 2018, time=2018-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339856, encodeId=0a07339856be, content=是说老了,胖点就无所谓了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Tue Aug 21 07:02:06 CST 2018, time=2018-08-21, status=1, ipAttribution=)]
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    2018-08-21 惠映实验室

    学习了,谢谢分享。

    0

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    2018-08-21 太阳系小猪

    是说老了,胖点就无所谓了吗?

    0

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