Brit J Surg:甲状腺髓样癌患者术后并发症

2020-11-24 MedSci原创 MedSci原创

MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。

手术是甲状腺髓样癌(MTC)患者的根治手段。在确定手术范围时,应考虑并发症风险。近日,外科疾病领域权威杂志British Journal of Surgery上发表了一篇研究文章,这项研究旨在评估MTC术后并发症的手术特异性结局和危险因素。

研究人员在两个欧洲前瞻性质量数据库中确定了接受甲状腺手术的MTC患者。甲状旁腺功能减退症是通过补钙/活性维生素D治疗来确定。喉镜检查可诊断出喉返神经麻痹。如果在最后一次随访中发生并发症,则至少是暂时的。研究人员通过Logistic回归分析确定了至少一次短暂性甲状旁腺功能低下和RLN麻痹的危险因素。

该研究共纳入了650名患者,这些患者分布在69个中心接受了手术,中位年龄为56岁。分别有170名(26.2%)、62名(13.7%)和17名(2.6%)患者出现甲状旁腺功能低下、RLN麻痹和需要再次手术的出血。与甲状旁腺功能低下有关的因素包括中央淋巴结清扫术(CLND)(比值比(OR)为2.20,95%CI为1.04至4.67)、CLND加上单侧外侧淋巴结清扫术(LLND)(OR为2.78,1.20至6.43)、CLND加双侧LLND(OR为2.83,1.13至7.05)和观察到四个或更多甲状旁腺(OR为4.18,1.46至12.00)。RLN麻痹与CLND加LLND(OR为4.04,1.12至14.58)和T4肿瘤(OR为12.16,4.46至33.18)相关。隔室定向淋巴结清扫后,537例患者中有248例达到N0状态(46.2%)。

由此可见,MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。

原始出处:

J. van Beek,et al.Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE databases.British Journal of Surgery.2020.https://bjssjournals.onlinelibrary.wiley.com/doi/10.1002/bjs.12055

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1758297, encodeId=e0c41e58297ee, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Fri Mar 19 21:26:12 CST 2021, time=2021-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822009, encodeId=5dc31822009ff, content=<a href='/topic/show?id=26091021157a' target=_blank style='color:#2F92EE;'>#髓样癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102115, encryptionId=26091021157a, topicName=髓样癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sat Jan 02 13:26:12 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910217, encodeId=0c9791021ee7, content=这种并发症是都会出现还是有个体差异性?, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31745400749, createdName=ms6000001296915076, createdTime=Tue Dec 22 22:36:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902375, encodeId=cb259023e52c, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。<a href='/topic/show?id=bec66989e9a' target=_blank style='color:#2F92EE;'>#甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=181, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69897, encryptionId=bec66989e9a, topicName=甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210325/2d9c955949df4b349a439f1a6773499e/b39f4845e869489d95bc545c79cf60fa.jpg, createdBy=303f5433779, createdName=Oranhyg, createdTime=Thu Nov 26 08:24:18 CST 2020, time=2020-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902207, encodeId=998690220e33, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Wed Nov 25 15:55:34 CST 2020, time=2020-11-25, status=1, ipAttribution=)]
    2021-03-19 丁鹏鹏
  2. [GetPortalCommentsPageByObjectIdResponse(id=1758297, encodeId=e0c41e58297ee, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Fri Mar 19 21:26:12 CST 2021, time=2021-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822009, encodeId=5dc31822009ff, content=<a href='/topic/show?id=26091021157a' target=_blank style='color:#2F92EE;'>#髓样癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102115, encryptionId=26091021157a, topicName=髓样癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sat Jan 02 13:26:12 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910217, encodeId=0c9791021ee7, content=这种并发症是都会出现还是有个体差异性?, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31745400749, createdName=ms6000001296915076, createdTime=Tue Dec 22 22:36:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902375, encodeId=cb259023e52c, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。<a href='/topic/show?id=bec66989e9a' target=_blank style='color:#2F92EE;'>#甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=181, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69897, encryptionId=bec66989e9a, topicName=甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210325/2d9c955949df4b349a439f1a6773499e/b39f4845e869489d95bc545c79cf60fa.jpg, createdBy=303f5433779, createdName=Oranhyg, createdTime=Thu Nov 26 08:24:18 CST 2020, time=2020-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902207, encodeId=998690220e33, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Wed Nov 25 15:55:34 CST 2020, time=2020-11-25, status=1, ipAttribution=)]
    2021-01-02 Boyinsh
  3. [GetPortalCommentsPageByObjectIdResponse(id=1758297, encodeId=e0c41e58297ee, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Fri Mar 19 21:26:12 CST 2021, time=2021-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822009, encodeId=5dc31822009ff, content=<a href='/topic/show?id=26091021157a' target=_blank style='color:#2F92EE;'>#髓样癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102115, encryptionId=26091021157a, topicName=髓样癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sat Jan 02 13:26:12 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910217, encodeId=0c9791021ee7, content=这种并发症是都会出现还是有个体差异性?, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31745400749, createdName=ms6000001296915076, createdTime=Tue Dec 22 22:36:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902375, encodeId=cb259023e52c, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。<a href='/topic/show?id=bec66989e9a' target=_blank style='color:#2F92EE;'>#甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=181, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69897, encryptionId=bec66989e9a, topicName=甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210325/2d9c955949df4b349a439f1a6773499e/b39f4845e869489d95bc545c79cf60fa.jpg, createdBy=303f5433779, createdName=Oranhyg, createdTime=Thu Nov 26 08:24:18 CST 2020, time=2020-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902207, encodeId=998690220e33, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Wed Nov 25 15:55:34 CST 2020, time=2020-11-25, status=1, ipAttribution=)]
    2020-12-22 ms6000001296915076

    这种并发症是都会出现还是有个体差异性?

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1758297, encodeId=e0c41e58297ee, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Fri Mar 19 21:26:12 CST 2021, time=2021-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822009, encodeId=5dc31822009ff, content=<a href='/topic/show?id=26091021157a' target=_blank style='color:#2F92EE;'>#髓样癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102115, encryptionId=26091021157a, topicName=髓样癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sat Jan 02 13:26:12 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910217, encodeId=0c9791021ee7, content=这种并发症是都会出现还是有个体差异性?, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31745400749, createdName=ms6000001296915076, createdTime=Tue Dec 22 22:36:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902375, encodeId=cb259023e52c, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。<a href='/topic/show?id=bec66989e9a' target=_blank style='color:#2F92EE;'>#甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=181, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69897, encryptionId=bec66989e9a, topicName=甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210325/2d9c955949df4b349a439f1a6773499e/b39f4845e869489d95bc545c79cf60fa.jpg, createdBy=303f5433779, createdName=Oranhyg, createdTime=Thu Nov 26 08:24:18 CST 2020, time=2020-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902207, encodeId=998690220e33, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Wed Nov 25 15:55:34 CST 2020, time=2020-11-25, status=1, ipAttribution=)]
    2020-11-26 Oranhyg

    MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。#甲状腺癌#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1758297, encodeId=e0c41e58297ee, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Fri Mar 19 21:26:12 CST 2021, time=2021-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822009, encodeId=5dc31822009ff, content=<a href='/topic/show?id=26091021157a' target=_blank style='color:#2F92EE;'>#髓样癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102115, encryptionId=26091021157a, topicName=髓样癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Sat Jan 02 13:26:12 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910217, encodeId=0c9791021ee7, content=这种并发症是都会出现还是有个体差异性?, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31745400749, createdName=ms6000001296915076, createdTime=Tue Dec 22 22:36:35 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902375, encodeId=cb259023e52c, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。<a href='/topic/show?id=bec66989e9a' target=_blank style='color:#2F92EE;'>#甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=181, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69897, encryptionId=bec66989e9a, topicName=甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210325/2d9c955949df4b349a439f1a6773499e/b39f4845e869489d95bc545c79cf60fa.jpg, createdBy=303f5433779, createdName=Oranhyg, createdTime=Thu Nov 26 08:24:18 CST 2020, time=2020-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=902207, encodeId=998690220e33, content=MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220301/6252e946e5ef413b86dc0f7d1f73b6db/9a7e8c88a38e487b8da4968a67bbd261.png, createdBy=b9f692910, createdName=rayms, createdTime=Wed Nov 25 15:55:34 CST 2020, time=2020-11-25, status=1, ipAttribution=)]
    2020-11-25 rayms

    MTC术后并发症是手术特异性的,可能与某些患者需要进行根治性切除不可避免的结果有关。

    0

相关资讯

Brit J Surg:甲状腺髓样癌术后并发症分析

MTC的术后并发症是特异性的,可能与某些患者需要进行根治性切除不可避免的结局相关。

Brit J Surg:全胰腺切除术后严重术后并发症的风险模型

由此可见,该风险模型可用于预测全胰腺切除术后的严重并发症。

胃造瘘术后并发症的观察和处理

经皮内镜下胃造瘘(percutaneous endoscopic gastrostomy, PEG )是肠内营养的实施手段之一,主要适用于因需要长期接受营养支持的患者或无法经口进食者。

Retina:25-GAUGE 玻璃体切除术术后低眼压发生率和危险因素研究

以色列Rambam医疗保健园区眼科的Mimouni M等人近日在Retina杂志上发表一篇文章。在非扩张性内膜情况下进行睫状体玻璃体切除术易引起低眼压症状,而这项研究的目的是评估25-gauge对术后早期低眼压的影响,评估其发生率和危险因素。

李晓东:大血管疾病腔内治疗,在实践中不断探索,寻求治疗更佳方案

腔内治疗在国内外如火如荼地开展,术后并发症的处理也是不容忽视的问题。特邀宁夏医科大学总医院李晓东教授分享他们在大血管疾病腔内治疗中,为了优化手术效果,减少术后并发症,进行的一些探索。

冠心病PCI术后并发症的风险与对策

近年来,冠脉介入(PCI)技术的成熟和广泛应用,降低了冠心病的死亡率,但同时存在着冠状动脉的再狭窄的可能。