NEJM:Apgar评分与早产儿新生儿死亡风险

2020-07-02 MedSci原创 MedSci原创

在5分钟和10分钟时的Apgar评分为不同胎龄早产儿新生儿的生存提供了的预后信息。

妊娠年龄是早产儿新生儿死亡(出生后28天之内死亡)的主要决定因素。胎龄和Apgar评分对新生儿死亡风险的联合影响尚不清楚。

近日,顶级医学期刊NEJM上发表了一篇研究文章,研究人员使用瑞典医疗出生登记处的数据确定了1992年至2016年期间出生的113300例早产儿(22周0天至36周6天)。在根据胎龄(22至24周、25至27周、28至31周、32至34周以及35或36周)进行的分层分析中,研究人员根据5分钟和10分钟的Apgar评分以及5分钟和10分钟之间Apgar评分的变化值估计了调整后的新生儿死亡相对风险和新生儿死亡的绝对比率差异(即,每100例新生儿死亡的额外数目)。Apgar评分从0到10不等,分数越高表示新生儿的身体状况越好。

1986名新生儿死亡(1.8%)。新生儿死亡的发生率处于0.2%(妊娠36周时)至76.5%(妊娠22周时)之间。Apgar分数越低,在所有胎龄的新生儿死亡相对风险越高,新生儿死亡率的绝对率差异越大。例如,以9或10得分的婴儿为参照组,在28到31周出生的婴儿中,根据5分钟Apgar评分为0或1的婴儿调整后的绝对率差异为51.7(95%置信区间[ CI]为38.1至65.4),得分为2或3的婴儿为25.5(95%CI为18.3至32.8),得分为4到6的婴儿为7.1(95%CI为5.1至9.1),得分为7或8的婴儿为1.2(95%CI为0.5至1.9)。Apgar评分在5分钟到10分钟之间的增加与较低的新生儿死亡率相关。

在这项研究中,在5分钟和10分钟时的Apgar评分为不同胎龄早产儿新生儿的生存提供了的预后信息。

在线使用:新生儿窒息评估(Apgar)评分法

原始出处:

Sven Cnattingius.et al.Apgar Score and Risk of Neonatal Death among Preterm Infants.NEJM.2020.https://www.nejm.org/doi/full/10.1056/NEJMoa1915075

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    2020-08-26 14818eb4m67暂无昵称

    地方很近

    0

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    2020-07-02 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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