新冠疫苗前沿知识:mRNA疫苗、重组蛋白疫苗、腺病毒载体疫苗

2021-05-30 网络 网络

什么是好疫苗?

什么是好疫苗? 疫苗要有很高的有效性、安全性、可及性。有效性体现在疫苗是否能引起高水平、持久的体液免疫和细胞免疫,以及疫苗能否对变异株起到保护作用;安全性体现在不良反应微小可控,适合接种人群广;可及性体现在疫苗生产、运输、保存和分发接种的成本和操作难度低。 图1. 好的疫苗需要具备的特质 大会对国内外已用于大规模接种的疫苗进行了讨论和对比。评估得到的结论是,国内新冠疫苗安全性强于国外,但诱导的抗体水平相对弱于国外。目前,新冠疫苗接种率最高的国家仍然是以色列,该国国民已经基本达到群体免疫水平,而我国接种剂量虽然名列前茅,但因为人口基数大,目前全民一剂疫苗接种率在30%左右,两剂新冠疫苗的接种率大约为8.6%,距离群体免疫(>70%)仍有一定距离。 百花齐放,多种路线齐头并进 目前全球新冠疫苗开发有多种技术路线,我国采用的技术路线主要有五种,除了大家所熟知并已大范围接种的灭活病毒疫苗之外,还有腺病毒载体疫苗、重组蛋白疫苗、mRNA疫苗、纳米颗粒疫苗。其中陈薇院士团队和康希诺公司合作研发的五型腺病毒载体疫苗,以及中科院微生物所和安徽智飞生物合作研发的RBD Dimer重组蛋白亚单位疫苗

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    2022-02-23 光明骑士

    优秀

    0

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    2021-08-15 mei539
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    2021-06-02 ms4000000879200649

    据说mRNA疫苗会和癌细胞产生作用,促进癌细胞生长,这是真的吗?有没有人在研究这个。

    0

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    2021-06-01 xqptu
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    2021-05-30 145b2d07m08暂无昵称

    mrna疫苗

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    2021-05-30 公卫新人

    新冠肺炎,疫情何时才能消失

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    2021-05-30 ms5000000698315053

    0

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