JACC:富含脂质与不富含脂质冠脉支架植入的预后比较研究

2020-03-26 MedSci原创 MedSci原创

尸检研究表明,在富含脂质斑块(LRP)的冠脉分支中植入支架可能与不良结局有关。本研究的目的是评价近红外光谱(NIRS)检测到的LRP与当代药物洗脱支架治疗冠心病患者的临床疗效之间的关系。

尸检研究表明,在富含脂质斑块(LRP)的冠脉分支中植入支架可能与不良结局有关。本研究的目的是评价近红外光谱(NIRS)检测到的LRP与当代药物洗脱支架治疗冠心病患者的临床疗效之间的关系。

本研究纳入分析了COLOR临床研究中的1999名接受了冠脉造影和可能经皮冠脉介入治疗(PCI)的患者,其中1621名患者接受了PCI治疗,在2年的随访时间中,有18%患者发生了主要不良心血管事件(MACE)。9例(0.45%)患者出现近红外成像并发症,导致1例围手术期心肌梗死和1例急诊冠状动脉搭桥。有1189名患者进行了PCI术前NIRS检测,2年的MACE与脂质斑块无明显相关性。

研究结果显示,在接受药物洗脱支架治疗的冠心病患者中,近红外光谱检测到的脂质斑块与患者的围手术期和术后不良预后不呈相关性。

原始出处:

Myong H et al.2-Year Outcomes After Stenting of Lipid-Rich and Nonrich Coronary Plaques.JACC.2020 Mar.

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    2020-11-15 hbwxf
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    2020-03-28 jiyangfei

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