JAHA:ST段抬高心肌梗死后发热的临床意义!

2017-04-26 xing.T MedSci原创

由此可见,心肌梗死后发热可以预测接受经皮冠状动脉介入治疗的ST段抬高性心肌梗死患者进一步的心肌损伤和较少的心肌挽救。

很少有关于ST段抬高心肌梗死患者梗死后发热与心肌损伤之间因果关系和病理机制的研究。近日,心血管疾病领域权威杂志JAHA上针对这一问题发表了一篇研究文章。

在276例接受经皮冠状动脉介入治疗的ST段抬高心肌梗死患者中,受试者在血管手术后平均3.4天进行心脏磁共振成像检查。45例患者发生心肌梗死后发热(发热组在经皮冠状动脉介入治疗4天内最高体温≥37.7°C),而231例没有发热(不发热组)。该研究的主要结局为通过心脏磁共振成像评估的心肌梗死大小。该研究的次要结局为危险面积程度、心肌挽救指数和微血管阻塞面积。

在心脏磁共振成像分析中,发热组的心肌梗死面积(发热组为25.6%[19.7-32.4] vs. 不发热组为17.2%[11.8-25.4];P<0.01)、危险面积程度(43.7%[31.9-54.9] vs. 35.3%[31.9-35.3];P<0.01)和微血管阻塞面积(4.4%[0.0-13.2] vs. 1.2% [0.0-5.1];P=0.02)均大于不发热组。发热组的心肌挽救指数往往较不发热组较低(37.7[28.5-56.1] vs. 47 [34.1-56.8];P=0.13)。在多变量分析中,心肌梗死后发热与较大的心肌梗死面积(比值比为3.48;95%可信区间为1.71-7.07;P<0.01)和较低的MSI(比值比为2.10;95%可信区间为1.01-4.08;P=0.03)相关。

由此可见,心肌梗死后发热可以预测接受经皮冠状动脉介入治疗的ST段抬高性心肌梗死患者进一步的心肌损伤和较少的心肌挽救。

原始出处:

Woo Jin Jang,et al. Clinical Significance of Postinfarct Fever in ST‐Segment Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study.JAHA.2017. https://doi.org/10.1161/JAHA.117.005687

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    2017-04-28 zhaohui6731
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    2017-04-28 gdsun
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    2017-04-28 hyf035
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    2017-04-26 flysky120

    很有意义的文章,学习

    0

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    2017-04-26 雅文博武

    学习了许多先进的医学知识

    0

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