Eur Arch Otorhinolaryngol:鼻内类固醇对常年过敏性鼻炎患者的鼻炎症状、睡眠质量和生活质量的影响

2021-05-06 AlexYang MedSci原创

最近,有研究人员评估了常年过敏性鼻炎(PAR)对健康相关生活质量(HRQL)的影响,衡量了PAR患者主要关注的问题,以及确定了鼻内类固醇(INS)对PAR和相关的鼻塞、睡眠障碍和白天嗜睡的影响。

最近,有研究人员评估了常年过敏性鼻炎(PAR)对健康相关生活质量(HRQL)的影响,衡量了PAR患者主要关注的问题,以及确定了鼻内类固醇(INS)对PAR和相关的鼻塞、睡眠障碍和白天嗜睡的影响

研究是一项横断面研究,共有78名PAR患者接受了耳鼻喉科检查和皮肤测试。所有参与者都填写了夜间鼻结膜炎生活质量调查表(NRQLQ)、斯坦福睡眠量表(SSS)和埃普沃斯睡眠量表(ESS)。参与者接受了布地奈德(BUD)外用水基鼻喷雾剂的治疗,为期8周。治疗期结束后,所有参与者再次回答上述三份调查问卷。

研究结果发现,在INS治疗后,NRQLQ总分(P<0.001)和单个NRQLQ模块得分(P<0.05)有统计学意义的显著改善。治疗前后NRQLQ四个领域的症状严重程度有统计学意义的显著降低(p<0.05),不包括烦躁不安、鼻后滴漏和避免症状触发(p分别为0.575、0.172和0.705)。另外,治疗前后的ESS和SSS评分有明显的统计学显著差异(P<0.001)。

BUD治疗前后NRQLQ不同模块得分的均差和标准差

最后,研究人员指出,PAR对睡眠质量有很大影响,QOL也较低。INS是治疗PAR的有效方式,能够通过改善鼻部症状、日间疲劳和嗜睡以及睡眠质量对患者的QOL产生积极影响

原始出处:

Marwa Abdelhafeez. Effectiveness of intranasal steroids on rhinitis symptoms, sleep quality, and quality of life in patients with perennial allergic rhinitis. Eur Arch Otorhinolaryngol. Apr 2021

 

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    2021-05-06 ms6000000242587021

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