JACC:血栓抽吸不能改善高血栓风险STEMI患者预后

2018-09-29 MedSci MedSci原创

常规的血栓抽吸对接受经皮冠脉介入治疗(PCI)的ST段抬高型心梗(STEMI)患者来说并不会改善预后,但对有高血栓风险的该类患者来说是否有益尚不清楚。本研究的目的旨在评估血栓抽吸对伴高血栓风险的STEMI患者是否有益。本研究纳入的是TOTAL临床研究中的STEMI患者,主要终点事件是心源性死亡、心梗、心源性休克和心衰。分析结果显示,1年主要终点事件在接受血栓抽吸的高血栓风险STEMI患者和不接受抽

常规的血栓抽吸对接受经皮冠脉介入治疗(PCI)的ST段抬高型心梗(STEMI)患者来说并不会改善预后,但对有高血栓风险的该类患者来说是否有益尚不清楚。本研究的目的旨在评估血栓抽吸对伴高血栓风险的STEMI患者是否有益。

本研究纳入的是TOTAL临床研究中的STEMI患者,主要终点事件是心源性死亡、心梗、心源性休克和心衰。分析结果显示,1年主要终点事件在接受血栓抽吸的高血栓风险STEMI患者和不接受抽吸的患者中无明显差异(8.1% vs. 8.3% [HR]: 0.97; 95% [CI]: 0.84 - 1.13),然而,在高血栓风险的患者中,30天的卒中发生率在血栓抽吸患者中更频繁,血栓抽吸不能改变患者30天和1年的心源性死亡率。另外,高血栓风险是死亡的独立预测因素(HR: 1.78; 95% CI: 1.05 - 3.01)。

研究结果显示,常规的血栓抽吸治疗不会改善高血栓风险的ST段抬高型心梗患者的预后,反而会增加卒中的发生风险。

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    2019-07-21 hbwxf
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    2018-09-29 liumin1987

    嗯嗯,学习了。

    0

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