2021年11月24日简报:新冠病毒跨物种传播,引发持续变异,结果好坏尚难预测;欧洲区域累计新冠死亡病例明年3月或超220万例;新西兰宣布放弃清零政策,与病毒共存;

2021-11-24 MedSci整理 MedSci整理

截至北京时间2021年11月24日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎(COVID-19)病例超过2亿5895万例,新增513,391例,达到258,957,

截至北京时间2021年11月24日7时01分,Worldometers世界实时统计数据显示,全球累计确诊新冠肺炎COVID-19)病例超过2亿5895万例,新增513,391例,达到258,957,384例。累计死亡病例518.1万例,达到5,181,573例。新增死亡为4,855例。康复为234,262,983例,重症和危重症病人达到81,582例;全球新冠确诊病例超过100万例的国家达36个,112个国家病例超10万例。昨日报道:2021年11月23日简报:中国研发的中和抗体能降低78%的住院和死亡率,有望年底上市;美前卫生局长警告称美新冠病例今冬或激增

世卫:欧洲区域累计新冠死亡病例明年3月或超220万例

当地时间23日,世界卫生组织欧洲区域办事处发表声明说,根据模型推演,2022年3月欧洲区域累计新冠死亡病例可能超过220万例。为此,各国政府和民众应负起责任,加大新冠疫苗接种力度,并继续采取戴口罩等防疫措施。

新西兰宣布放弃清零政策,并采取“与病毒共存”的新抗疫策略

当地时间11月22日,由于国内疫情迟迟不见好转,新西兰总理杰辛达·阿德恩在内阁新闻发布会上正式宣布,自12月2日午夜起,该国将放弃病例“清零”政策,并采取“与病毒共存”的新抗疫策略。

在内阁新闻发布会上,阿德恩表示,鉴于目前的疫情形势,新西兰的防疫策略将从原来的“清零”政策转变为“与新冠共存”的抗疫政策。对于当前新西兰面临的疫情形势,阿德恩直言,“没有哪个国家能够完全消灭德尔塔毒株,但新西兰比绝大多数国家更加具有迎接挑战的准备”。

她还表示,在经历了长达3个多月的封城措施后,该国最大城市奥克兰也即将在12月15日解封。据悉,自新冠疫情出现起,新西兰政府就采取了一系列措施,包括地区封锁、病例追踪、出入境管控等严格的防疫措施,试图利用新西兰独特的地理位置将该国病例“清零”。

截至11月22日下午1时,新西兰新冠肺炎累计确诊病例达10176例,累计死亡病例40例。值得注意的是,在过去24小时里,新西兰国内的确诊病例就新增了205例,而且大都集中在该国封锁措施中最严的奥克兰市。

SARS-CoV-2在跨物种传播中存在大量单核苷酸和结构变异,结果好坏难预测

此前,我国学者研究表明,新冠病毒的N501Y突变,能够赋予其跨物种传播的能力,并提出小鼠作为新冠病毒进行传播的潜在中间宿主的可能性。美国野生白尾鹿的淋巴结样本,发现80%样本感染了新冠病毒。如果这些病毒再回传到人,形成跨物种传播,可能会引发新的危机可能。

在所有的16个数据集中共观察到了 270 次突变,包括242 个单核苷酸变异(SNV)和 28 个结构变异(SV;插入和缺失)。其中有 88 个独特的突变,这包括 74 个 SNV 和 14 个 SV。并且检测到 25% 或更高的频率的突变71 个(26.3%)。

另外研究者发现一个奇怪的现象,有7个新冠病毒 的SNV从一个或多个物种中发现,而且其发生在与人类或其他物种的变异相一致的位置。这一位置很可能是病毒适应性传播的关键位点,值得科学家们高度关注。

此项研究报告了在细胞培养和非人类哺乳动物宿主(包括狗和猫)感染后,大量新冠病毒变异的惊人快速选择。新冠病毒的这些分子变化为了解病毒宿主适应机制提供了依据,为进一步研究显性变异的适应度和表型奠定了基础,并突出了与人类密切和频繁接触的物种产生的新病毒变异在人类中再次感染的可能性

国际著名病毒学家彼得 皮奥特认为抗击新冠需要有长期思维

国际著名病毒学家彼得 皮奥特(Peter Piot),聚焦欧洲疫情与全球抗疫等问题进行探讨。

彼得 皮奥特认为,新冠疫情已经持续了将近2年的时间,目前看来疫情短期内不会立马消失。我们可能会遇到像流感一样的情况,每年冬季的病例会有所上升,但由于接种疫苗、戴口罩等其他措施,感染病例、重症病例以及死亡病例都会越来越少。因此,我们需要有长期思维,经济发展和民众生活都受新冠疫情影响的情况下,我们要为整个社会找到应对疫情的最佳方式。

欧洲再成全球新冠疫情“震中”反防疫示威却持续不断

据美国《纽约时报》报道,近期,欧洲再次成为全球新冠疫情的“震中”,每周新增病例数超过200万例,达到了疫情暴发以来的最高水平。随着新冠疫苗接种率的下降和冬季的临近,越来越多的欧洲国家开始敲响警钟,收紧新冠肺炎的防疫措施。

德国卫生部长延斯·施潘(Jens Spahn)警告称,基本上所有德国人到今冬结束时“要么完成了疫苗接种,要么已经康复,要么失去生命”。他在新闻发布会上说:“群体免疫会实现,但问题是,到底是通过接种疫苗还是通过感染病毒的方式实现。我们明确建议,通过打疫苗的方式。”

当地时间11月22日,奥地利启动大规模“封城”举措,成为西欧首个再次实施全国范围“封城”的国家。除上班、采购日常生活用品和运动外,居民不得外出。多数店铺、剧院、理发店和圣诞市场关门;餐馆和咖啡厅禁止堂食;学校不停课,但政府建议学生居家上课。

然而,由于不满政府的防疫措施,包括奥地利、荷兰、比利时、丹麦等欧洲多国出现示威游行。期间还发生多起暴力事件,警察动用了催泪瓦斯和高压水枪。当地时间22日,荷兰首相吕特强烈谴责连日来荷兰多个城市反防疫示威中的暴力行为,称这些暴力行径是“愚蠢”的,完全不能接受。

美国对赴德国丹麦旅行发布最高级别警告

美国疾控中心(CDC)当天将对德国、丹麦两国的新冠疫情评估提升至最高级别第四级,认为两国“疫情水平非常高”,并建议避免赴这两国旅行,如必须前往,应确保出行前完成新冠疫苗接种。

欧洲近期再次成为全球新冠疫情“震中”。德国、英国等多国单日新增确诊病例数居高不下,奥地利22日起再次实施全国“封城”以遏制疫情。美国务院本月早些时候已把对荷兰、匈牙利、捷克、冰岛等欧洲国家的旅行建议调至最高警告级别。

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    2022-10-25 respect
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    2021-11-25 bioon3
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    2021-11-24 查查佳佳

    郁症状与心力衰竭(HF)的风险增加相

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    2021-11-24 moyanju2796

    学习了

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