Stroke:识别急性脑桥梗死的神经功能障碍相关因素

2020-07-11 shaosai MedSci原创

关于急性脑桥梗死患者梗死灶形态与神经功能障碍间的关系尚不明确。本研究旨在识别急性脑桥梗死早期神经功能障碍(END)的形态学MRI预测指标。

背景与目的

关于急性脑桥梗死患者梗死灶形态与神经功能障碍间的关系尚不明确。本研究旨在识别急性脑桥梗死早期神经功能障碍(END)的形态学MRI预测指标。

方法

本研究纳入了脑桥急性缺血性脑梗死的患者。腹背侧长度及宽度做梗死大小。END定义为在发病后1周内NIHSS评分增加运动力≥1分或总分≥2分。


结果

本研究共纳入了407例患者,其中有114(28%)例患者诊断为END

。经调整logistic回归分析显示最长径与厚度乘积是预测END的独立指标。ROC曲线分析中最长径与厚度乘积预测END的敏感性、特异性和曲线下面积分别为77.2%、79.2%和 0.843。

结论

本研究结果表明最大长度与厚度乘积可能是预测单纯性急性脑桥梗死的独立指标。脑桥梗死沿传导束的范围可能是导致神经功能障碍的原因。

原始出处:

Li H, Dai Y, Wu H et al. Predictors of Early Neurologic Deterioration in Acute Pontine Infarction.DOI: 10.1161/STROKEAHA.119.027239

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    2020-11-18 amy0560
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    2020-07-18 jin321

    临床难度大

    0

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    2020-07-11 lovetcm

    #卒中#进一步分部位

    0

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