Gastric cancer :大于75岁的老年胃癌患者行非治愈性内镜黏膜下剥离的远期疗效和预后因素分析

2019-10-21 不详 MedSci原创

对于早期胃癌的老年患者,非治愈性内镜黏膜下剥离术(ESD)的长期结果和预后因素知之甚少。本项研究旨在对其进行一些探讨。

背景
对于早期癌的老年患者,非治愈性内镜黏膜下剥离术(ESD)的长期结果和预后因素知之甚少。本项研究旨在对其进行一些探讨。

方法
研究人员收集了87例接受了非治愈性ESD治疗的年龄≥75岁的早期癌(EGC)患者,评估了其临床病理结果和长期疗效。使用Kaplan-Meier方法和Cox比例风险模型分析了总生存期(OS)的预后因素。

结果
在随访期间,在因任何原因死亡的27名患者中,只有一名患者死于胃癌。3年和5年后的OS概率分别为89.7%和79.3%。单因素分析显示, Charlson合并症指数(CCI)≥3,中性粒细胞/淋巴细胞比≥3.3,预后营养指数<44.8,远端肿瘤的位置以及宏观上的抑郁或扁平形态与OS差相关。Cox多变量分析显示,高CCI(≥3)是与OS相关的独立预后因素(危险比:2.63,95%置信区间[CI] 1.06-6.49,P= 0.037)。

结论
行非治愈性ESD治疗的老年胃癌患者在进行其他手术时,CCI指数可能使有用的参数。

原始出处:

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    2020-03-19 skhzy
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1893655, encodeId=4fc2189365594, content=<a href='/topic/show?id=4fc4e85161' target=_blank style='color:#2F92EE;'>#gastric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7851, encryptionId=4fc4e85161, topicName=gastric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Thu Mar 19 01:45:00 CST 2020, time=2020-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769683, encodeId=f5eb1e6968374, content=<a href='/topic/show?id=900b8323461' target=_blank style='color:#2F92EE;'>#胃癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83234, encryptionId=900b8323461, topicName=胃癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=377c38086944, createdName=huhuaidong400, createdTime=Sun Jul 19 20:45:00 CST 2020, time=2020-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723738, encodeId=6a1e1e237385d, content=<a href='/topic/show?id=abb8944281f' target=_blank style='color:#2F92EE;'>#远期疗效#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94428, encryptionId=abb8944281f, topicName=远期疗效)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bdbd33532298, createdName=karmond, createdTime=Wed Oct 30 12:45:00 CST 2019, time=2019-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2072749, encodeId=af8020e274947, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Mar 21 09:45:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712150, encodeId=aa371e12150ca, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon May 04 20:45:00 CST 2020, time=2020-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1262136, encodeId=069f126213684, content=<a href='/topic/show?id=0ceb30545e0' target=_blank style='color:#2F92EE;'>#内镜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30545, encryptionId=0ceb30545e0, topicName=内镜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Wed Oct 23 02:45:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1479297, encodeId=841514e9297e3, content=<a href='/topic/show?id=8c141001e8c6' target=_blank style='color:#2F92EE;'>#预后因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100178, encryptionId=8c141001e8c6, topicName=预后因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=49d37510120, createdName=ms2536978994064944, createdTime=Wed Oct 23 02:45:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520044, encodeId=02f9152004484, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Wed Oct 23 02:45:00 CST 2019, time=2019-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032311, encodeId=92de1032311d8, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Mon Oct 21 14:45:00 CST 2019, time=2019-10-21, status=1, ipAttribution=)]
    2020-03-21 许安
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    2019-10-23 snowpeakxu
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    2019-10-21 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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