Ann Intern Med:针灸可有效缓解慢性前列腺炎/慢性盆腔疼痛综合征患者的疼痛

2021-11-27 Nebula MedSci原创

8周内予以20次针灸治疗可很好的改善中重度慢性前列腺炎/慢性盆腔疼痛综合征患者的疼痛症状,而且效果持久

慢性前列腺炎/慢性盆腔疼痛综合征 (CP/CPPS) 涉及泌尿生殖系统疼痛、下尿路症状、心理问题和性功能障碍。它影响高收入国家2%-16%的人口,影响低-中等收入国家11%的人口。CP/CPPS对生活质量的负面影响可堪比心绞痛、心肌梗死、充血性心力衰竭、糖尿病和克罗恩病。

针灸对慢性前列腺炎/慢性盆腔疼痛综合征(CP/CPPS)有很好的疗效,但缺乏高质量的证据。本研究旨在评估采用针灸治疗CP/CPPS的长期疗效。

这是一项多中心、随机、假对照的临床试验,招募了中重度CP/CPPS患者(无论既往是否接受过针灸治疗)。予以为期8周共20个疗程的针灸或假针灸治疗,治疗后持续随访24周。主要终点是应答者的比例:即第8周和第32周时疼痛明显减轻的患者比例(慢性前列腺炎症状指数至少较基线降低6分)。

两组应答者的比例

共招募了440位男性(每组各220位)。第8周时,针灸组和假针灸组的应答者比例分别是60.6%和36.8%(校正差 21.6%;校正优势比 2.6;p<0.001)。第32周时,针灸组和假针灸组的应答率分别是61.5%和38.3%(校正差 21.1%;校正优势比 2.6;p<0.001)。

两组患者NIH-CPSI总评分的平均变化

针灸组和假针灸组分别报告了20例(9.1%)和14例(6.4%)不良反应事件。无严重不良反应事件。

综上,与假治疗相比,8周内予以20次针灸治疗可更好的改善中重度慢性前列腺炎/慢性盆腔疼痛综合征患者的疼痛症状,并在治疗结束后效果可维持24周之久。

原始出处:

Sun Yuanjie,Liu Yan,Liu Baoyan et al. Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome : A Randomized Trial.[J] .Ann Intern Med, 2021, https://doi.org/10.7326/M21-1814

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    2022-10-11 anan
  2. [GetPortalCommentsPageByObjectIdResponse(id=1945934, encodeId=dd8f19459345c, content=<a href='/topic/show?id=67dfe221920' target=_blank style='color:#2F92EE;'>#盆腔疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72219, encryptionId=67dfe221920, topicName=盆腔疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=236b481, createdName=anan, createdTime=Tue Oct 11 11:45:48 CST 2022, time=2022-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1205815, encodeId=c7a71205815c9, content=坚持就有疗效, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48e46488127, createdName=ms3000000235780593, createdTime=Fri Mar 25 11:10:07 CST 2022, time=2022-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1077973, encodeId=da0010e7973b2, content=这倒是可以尝试, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqcKvRg31a63sZDpdAibIlvcmic3YEBVp1tyyp1O1ViajV2742nZfWXS8JjIJrnBjlvnY4xdW69ZH53g/132, createdBy=207c5097942, createdName=尿尿尿不到, createdTime=Wed Dec 08 07:37:19 CST 2021, time=2021-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432201, encodeId=34fe1432201f1, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611347, encodeId=eb40161134e77, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074713, encodeId=7b9c10e4713b7, content=学习了。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1bc5420323, createdName=wanyych, createdTime=Sun Nov 28 09:35:36 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074695, encodeId=6e5910e4695fb, content=型肝炎的治疗方法因直接作用抗病毒, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sun Nov 28 07:46:00 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074681, encodeId=816310e468102, content=<a href='/topic/show?id=66ed9628563' target=_blank style='color:#2F92EE;'>#针灸#</a>对<a href='/topic/show?id=0a22325156f' target=_blank style='color:#2F92EE;'>#前列腺炎#</a>确实是有效的哦,主要缓解症状,对疾病影响还不可知, beContent=null, objectType=article, channel=null, level=null, likeNumber=175, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96285, encryptionId=66ed9628563, topicName=针灸), TopicDto(id=32515, encryptionId=0a22325156f, topicName=前列腺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sun Nov 28 07:21:28 CST 2021, time=2021-11-28, status=1, ipAttribution=)]
    2022-03-25 ms3000000235780593

    坚持就有疗效

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1945934, encodeId=dd8f19459345c, content=<a href='/topic/show?id=67dfe221920' target=_blank style='color:#2F92EE;'>#盆腔疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72219, encryptionId=67dfe221920, topicName=盆腔疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=236b481, createdName=anan, createdTime=Tue Oct 11 11:45:48 CST 2022, time=2022-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1205815, encodeId=c7a71205815c9, content=坚持就有疗效, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48e46488127, createdName=ms3000000235780593, createdTime=Fri Mar 25 11:10:07 CST 2022, time=2022-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1077973, encodeId=da0010e7973b2, content=这倒是可以尝试, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqcKvRg31a63sZDpdAibIlvcmic3YEBVp1tyyp1O1ViajV2742nZfWXS8JjIJrnBjlvnY4xdW69ZH53g/132, createdBy=207c5097942, createdName=尿尿尿不到, createdTime=Wed Dec 08 07:37:19 CST 2021, time=2021-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432201, encodeId=34fe1432201f1, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611347, encodeId=eb40161134e77, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074713, encodeId=7b9c10e4713b7, content=学习了。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1bc5420323, createdName=wanyych, createdTime=Sun Nov 28 09:35:36 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074695, encodeId=6e5910e4695fb, content=型肝炎的治疗方法因直接作用抗病毒, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sun Nov 28 07:46:00 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074681, encodeId=816310e468102, content=<a href='/topic/show?id=66ed9628563' target=_blank style='color:#2F92EE;'>#针灸#</a>对<a href='/topic/show?id=0a22325156f' target=_blank style='color:#2F92EE;'>#前列腺炎#</a>确实是有效的哦,主要缓解症状,对疾病影响还不可知, beContent=null, objectType=article, channel=null, level=null, likeNumber=175, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96285, encryptionId=66ed9628563, topicName=针灸), TopicDto(id=32515, encryptionId=0a22325156f, topicName=前列腺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sun Nov 28 07:21:28 CST 2021, time=2021-11-28, status=1, ipAttribution=)]
    2021-12-08 尿尿尿不到

    这倒是可以尝试

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1945934, encodeId=dd8f19459345c, content=<a href='/topic/show?id=67dfe221920' target=_blank style='color:#2F92EE;'>#盆腔疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72219, encryptionId=67dfe221920, topicName=盆腔疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=236b481, createdName=anan, createdTime=Tue Oct 11 11:45:48 CST 2022, time=2022-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1205815, encodeId=c7a71205815c9, content=坚持就有疗效, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48e46488127, createdName=ms3000000235780593, createdTime=Fri Mar 25 11:10:07 CST 2022, time=2022-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1077973, encodeId=da0010e7973b2, content=这倒是可以尝试, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqcKvRg31a63sZDpdAibIlvcmic3YEBVp1tyyp1O1ViajV2742nZfWXS8JjIJrnBjlvnY4xdW69ZH53g/132, createdBy=207c5097942, createdName=尿尿尿不到, createdTime=Wed Dec 08 07:37:19 CST 2021, time=2021-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432201, encodeId=34fe1432201f1, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611347, encodeId=eb40161134e77, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Nov 29 13:45:48 CST 2021, time=2021-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074713, encodeId=7b9c10e4713b7, content=学习了。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1bc5420323, createdName=wanyych, createdTime=Sun Nov 28 09:35:36 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074695, encodeId=6e5910e4695fb, content=型肝炎的治疗方法因直接作用抗病毒, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Sun Nov 28 07:46:00 CST 2021, time=2021-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1074681, encodeId=816310e468102, content=<a href='/topic/show?id=66ed9628563' target=_blank style='color:#2F92EE;'>#针灸#</a>对<a href='/topic/show?id=0a22325156f' target=_blank style='color:#2F92EE;'>#前列腺炎#</a>确实是有效的哦,主要缓解症状,对疾病影响还不可知, beContent=null, objectType=article, channel=null, level=null, likeNumber=175, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96285, encryptionId=66ed9628563, topicName=针灸), TopicDto(id=32515, encryptionId=0a22325156f, topicName=前列腺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Sun Nov 28 07:21:28 CST 2021, time=2021-11-28, status=1, ipAttribution=)]
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    2021-11-28 wanyych

    学习了。。

    0

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    2021-11-28 查查佳佳

    型肝炎的治疗方法因直接作用抗病毒

    0

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    2021-11-28 病毒猎手

    #针灸##前列腺炎#确实是有效的哦,主要缓解症状,对疾病影响还不可知

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