JACC:升主动脉长度与主动脉瘤患者预后相关

2019-10-20 不详 网络

升主动脉瘤的纵向变化少有人关注,本研究的目的旨在评估升主动脉瘤(ATAA)的自然病程以及升主动脉长度(AAL)。本研究纳入了522例ATAA患者,对其升主动脉直径、长度和远期不良主动脉事件(破裂、夹层和死亡)进行了评估。结果发现,与AAL<9 cm的患者相比,AAL≥13cm患者的不良主动脉事件发生风险要增高5倍以上。主动脉平均每年增长0.18cm,且与年龄呈独立相关。联合主动脉高度指数(A

升主动脉瘤的纵向变化少有人关注,本研究的目的旨在评估升主动脉瘤(ATAA)的自然病程以及升主动脉长度(AAL)。

本研究纳入了522例ATAA患者,对其升主动脉直径、长度和远期不良主动脉事件(破裂、夹层和死亡)进行了评估。结果发现,与AAL<9 cm的患者相比,AAL≥13cm患者的不良主动脉事件发生风险要增高5倍以上。主动脉平均每年增长0.18cm,且与年龄呈独立相关。联合主动脉高度指数(AHI)可以明显提高logistic回归模型的风险识别度,AHIs <9.33, 9.38-10.81, 10.86-12.50和≥12.57 cm/m与每年不良主动脉事件风险增加~4%, ~7%, ~12%和~18%相关。

研究结果显示,主动脉增长11cm可作为ATAA治疗的标准,主动脉高度指数是最佳的风险预测因子。

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    2020-01-24 hbwxf
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    2019-10-20 天地飞扬

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