J Cosmet Dermatol:中药调理霜可有效调理黄褐斑

2020-06-28 MedSci原创 MedSci原创

黄褐斑是一种后天性的、常见的面部色素沉着症。虽然目前治疗方法很多,但疗效一般。为了研究一种含有中草药混合物的膏药治疗黄褐斑的安全性和有效性。

黄褐斑是一种后天性的、常见的面部色素沉着症。虽然目前治疗方法很多,但疗效一般。为了研究一种含有中草药混合物的膏药治疗黄褐斑的安全性和有效性。

 

本次随机、双盲、对照临床研究共纳入90名黄褐斑志愿者,将他们随机分为三组(A、B、C)。A组患者使用含有中草药混合物的乳膏进行治疗,B组和C组分别使用熊果苷乳膏和安慰剂进行治疗,每天两次,持续12周。每4周评估一次黄褐斑面积和严重程度指数(MASI)评分、黑色素指数(MI)、红斑指数(EI)、炎症细胞密度变化和不良事件。

 

结果显示,虽然A组和B组的MASI评分均显著下降(P<0.05),但A组的下降幅度更大(A组13.00-9.82=3.18;B组12.65-10.84=1.81)。此外,含有中药混合物的乳膏,而不是熊果苷乳膏和安慰剂,在治疗12周后显著降低EI和炎症细胞的密度(P<0.05)。在B组中,有两名受试者出现了轻微的红斑和瘙痒,但在停止使用熊果苷霜后消失。

 

综上所述,该研究结果表明,说明本品为安全有效的黄褐斑膏剂。

 

原始出处:

 

Qiongyu ZhangYing Tu, et al., A Cream of Herbal Mixture to Improve Melasma. J Cosmet Dermatol. 2019 Dec;18(6):1721-1728. doi: 10.1111/jocd.12938. 

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    2020-10-05 tcm99hq
  2. [GetPortalCommentsPageByObjectIdResponse(id=1783631, encodeId=35071e8363154, content=<a href='/topic/show?id=f6c9511ec2' target=_blank style='color:#2F92EE;'>#CoSM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5117, encryptionId=f6c9511ec2, topicName=CoSM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=74c2229, createdName=tcm99hq, createdTime=Mon Oct 05 08:38:42 CST 2020, time=2020-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=922109, encodeId=297b92210938, content=中药混合物的主要成份有哪些?, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=316a5457720, createdName=ms1000002096857609, createdTime=Tue Feb 02 08:31:10 CST 2021, time=2021-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896689, encodeId=fabe189668907, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 23 17:38:42 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800583, encodeId=15398005835a, content=市场上有了吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f59a5397112, createdName=ms4000002045505932, createdTime=Tue Jun 30 14:16:46 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800167, encodeId=926380016e50, content=研究质量不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Sun Jun 28 22:45:27 CST 2020, time=2020-06-28, status=1, ipAttribution=)]
    2021-02-02 ms1000002096857609

    中药混合物的主要成份有哪些?

    0

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    2020-09-23 一闲
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    2020-06-30 ms4000002045505932

    市场上有了吗?

    0

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    2020-06-28 mswert122

    研究质量不好

    0

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