Menopause:一举两得!雌激素治疗绝经后女性骨质疏松还能降低牙周炎患病率

2017-07-24 吴刚 环球医学

绝经后女性由于雌激素减少会加速骨量的流失,使骨密度下降,极易引起骨质疏松症。2017年7月,发表在《Menopause》的一项研究调查了绝经后女性骨质疏松治疗和重症牙周炎之间的相关性。



绝经后女性由于雌激素减少会加速骨量的流失,使骨密度下降,极易引起骨质疏松症。2017年7月,发表在《Menopause》的一项研究调查了绝经后女性骨质疏松治疗和重症牙周炎之间的相关性。

目的:旨在评估绝经后女性中,骨质疏松治疗和重症牙周炎之间的相关性。

方法:该横断面研究由492名绝经后女性组成,其中的113人接受骨质疏松治疗,379人未接受。骨质疏松治疗由全身雌激素单独使用或雌激素+孕激素、钙和维生素D补充组成,至少治疗6个月。重症牙周炎的定义为至少两个临近的牙齿部位具有至少6mm的临床附着丧失,并且至少1个相邻部位具有至少5mm的探测深度;使用糜烂、缺失和填充牙(DMFT)指数测量龋齿经历。分析包括描述性统计和具有稳健方差的泊松多变量分析。

结果:接受骨质疏松治疗的女性比未接受治疗的女性具有较低的牙周探诊深度、较少的临床附着丧失、较少的牙龈出血(P≤0.05)。骨质疏松治疗组,估计平均DMFT指数评分约20,最常见的元素为缺失牙齿的数量;非治疗组,DMFT指数约19。骨质疏松治疗组比非治疗组的重症牙周炎的患病率低44%。调整了吸烟、年龄、家庭收入和牙科就诊后,调整的患病率为0.56,95% CI为0.31~0.99(P=0.05)。

结论:结果表明,雌激素治疗绝经后骨质疏松的女性比未接受治疗的女性具有较低的重症牙周炎患病率。

原始出处:

Passos-Soares JS, Vianna MIP, Gomes-Filho IS, et al. Association between osteoporosis treatment and severe periodontitis in postmenopausal women. Menopause. 2017 Jul;24(7):789-795. doi: 10.1097/GME.0000000000000830.

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    2017-08-12 hfuym10906

    学习了学习了学习了学习了学习了学习了

    0

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    2017-07-30 186****0580(小山羊)

    学习了谢谢了。

    0

  4. 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  8. 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    2017-07-26 Eleven17
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    2017-07-26 zxxiang

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Menopause:为何有些女性容易抑郁?

在绝经过渡期(MT)和初始绝经年——雌激素显著波动的两次,女性抑郁症的发生风险增加。迄今为止,关于雌激素波动在中年抑郁症易感性增加中起着重要作用这一假设的研究提供了有限的数据支持。重要的是,并非所有的妇女在MT期间会出现抑郁症状,近期的报告表明,成年期暴露于雌二醇的持续时间也可能在抑郁症易感性中起着一定的作用。本研究探讨了育龄期雌激素的暴露模式和MT期及绝经后早期的抑郁风险。研究共纳入了1306名

Sci Rep:雌激素可以促进自噬来抑制动脉钙化!

动脉钙化是心血管疾病的主要并发症。绝经后妇女的雌激素替代疗法与冠状动脉钙化水平相关,但其作用机制目前尚不清楚。近期,一项发表在杂志Sci Rep上的研究显示雌激素可以通过促进自噬来抑制体外血管平滑肌细胞(VSMC)的成骨细胞分化和体内动脉钙化。此项研究通过电子显微镜、GFP-LC3重新分布和免疫荧光分析以及自噬体标记轻链I / II(LC3I / II)和自噬蛋白5(Atg5)的表达测定,研究者们

Hum Mol Genet:喝茶到底好不好? 研究称对女性影响更大!

近日,瑞典乌普萨拉大学(Uppsala University)研究人员发现女性的饮茶习惯能够导致已知癌症和雌激素代谢相互作用相关基因的表观遗传变化,而表观遗传变化是能够引起我们基因发生表达终止和表达开启的重要化学修饰。该研究对应文章名为Tea and coffee consumption in relation to DNA methylation in four European cohorts

Hum Reprod:早期乳腺癌妇女应用控制性超排卵的安全性和有效性

研究问题:在不影响乳腺癌妇女预后的情况下,控制性超排卵(COH)能有效的进行生育力保存吗?

Clin Gastroenterol H:雌激素替代疗法降低女性肝癌患者的风险和增加生存时间!

在HCC与女性对照者的单中心病例对照研究中,研究人员发现使用雌激素与HCC风险降低以及增加HCC患者整体生存期相关。需要进一步的研究来确定雌激素治疗对妇女和HCC患者的好处,以及对肿瘤雌激素受体表达的影响。

胸大、胸小哪个更容易得乳腺癌?

现实生活中很多男生喜欢大胸妹子,而很多女生则认为“胸大有什么好的?胸大更容易的乳腺癌。”这一说法是真的吗?