2019年AAN:过继细胞疗法治疗进行性多灶性白质脑病

2019-05-13 不详 网络

2019年美国神经病学学会(AAN)年会上发表的一项研究证实,源自患者一级亲属的抗多瘤病毒特异性T细胞能够用来治疗PML。

进行性多灶性白质脑病(PML)是一种以进行性脑损伤和多灶性脑白质炎症为特点的罕见并致命的病毒性疾病。PML仅发生于严重免疫缺陷患者,例如接受免疫抑制药物的器官移植患者和接受特定化疗药物的患者。PML是由JC病毒感染所致,在免疫力正常的人群中JC病毒的感染能够被免疫系统所控制,而免疫缺陷病人往往不能抵抗JC病毒的侵袭。

2019年美国神经病学学会(AAN)年会上发表的一项研究证实,源自患者一级亲属的抗多瘤病毒特异性T细胞能够用来治疗PML。美国国立卫生研究院医学博士Erin Beck表示:在试验方案治疗的12名患者中,7名患者使用过继细胞疗法3次后幸存了下来,7名存活的患者也有神经功能的改善。4例在最后一次输注后30天内死亡


原始出处:

http://www.firstwordpharma.com/node/1640419#axzz5ngGcHmd9

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    2020-02-20 showtest
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    2019-05-15 bluefate123
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    2019-05-13 一个字-牛

    学习了谢谢分享

    0

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