JAHA:心力衰竭住院患者房颤负担的变化趋势

2021-05-20 MedSci原创 MedSci原创

AF在HF住院治疗患者中越来越普遍,并伴有更高的费用和住院死亡率。随着时间的推移,伴有AF的HF患者较年轻,白人患者可能性较小,合并症更多,住院死亡率降低。

心力衰竭(HF)和心房颤动(AF)经常并存,并可能与较差的HF结局相关,但当代证据不足,无法说明它们的合并患病率。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员评估了美国射血分数正常的HF(HFpEF)或射血分数降低的HF(HFrEF)患者住院治疗期间房颤的当前趋势,以及患者的结局和成本。

研究人员使用国家住院患者样本,从2008年至2017年期间确定了10392189例HF住院患者,其中4250698例(40.9%)患者合并有AF。伴有AF的HF住院治疗患者年龄较大(平均年龄为76.9岁 vs. 68.8岁),更可能是白人患者(77.8% vs. 59.1%;两者均P<0.001)。HFpEF患者比HFrEF患者合并AF的比例更高(44.9% vs. 40.8%)。

2008年至2017年HF患者死亡率

随着时间的推移,合并AF的比例从2008年的35.4%增加到2017年的45.4%,患者为年轻男性、黑人或西班牙裔。合并症高血压、糖尿病和血管疾病也随时间推移均有所增加。伴有AF的HF住院患者的院内死亡率高于无AF的患者住院死亡率(3.6% vs. 2.6%);所有HF的死亡率随时间推移有所降低(从3.6%降至3.4%),但射血分数降低的HF有所增加(从3.0%增至3.7%;对于所有HF,P<0.001)。伴有AF的HF患者中位住院费用较高,且随时间推移增加40%(从22204美元增至31145美元;P<0.001)。

由此可见,AF在HF住院治疗患者中越来越普遍,并伴有更高的费用和住院死亡率。随着时间的推移,伴有AF的HF患者较年轻,白人患者可能性较小,合并症更多,住院死亡率降低。未来的研究将需要解决不断变化的患者人口统计特征和成本上升的特点。

原始出处:

Samuel W. Reinhardt.et al.National Trends in the Burden of Atrial Fibrillation During Hospital Admissions for Heart Failure.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.019412

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1985735, encodeId=10381985e3561, content=<a href='/topic/show?id=bae250886c8' target=_blank style='color:#2F92EE;'>#心力衰竭住院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50886, encryptionId=bae250886c8, topicName=心力衰竭住院)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/656F31B644588474D1C46903A7F84373/100, createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Wed Jan 19 07:48:41 CST 2022, time=2022-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268538, encodeId=c15612685387e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat May 22 11:48:41 CST 2021, time=2021-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031388, encodeId=3223103138874, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Thu May 20 23:48:41 CST 2021, time=2021-05-20, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1985735, encodeId=10381985e3561, content=<a href='/topic/show?id=bae250886c8' target=_blank style='color:#2F92EE;'>#心力衰竭住院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50886, encryptionId=bae250886c8, topicName=心力衰竭住院)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/656F31B644588474D1C46903A7F84373/100, createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Wed Jan 19 07:48:41 CST 2022, time=2022-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268538, encodeId=c15612685387e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat May 22 11:48:41 CST 2021, time=2021-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031388, encodeId=3223103138874, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Thu May 20 23:48:41 CST 2021, time=2021-05-20, status=1, ipAttribution=)]
    2021-05-22 zhaohui6731
  3. [GetPortalCommentsPageByObjectIdResponse(id=1985735, encodeId=10381985e3561, content=<a href='/topic/show?id=bae250886c8' target=_blank style='color:#2F92EE;'>#心力衰竭住院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50886, encryptionId=bae250886c8, topicName=心力衰竭住院)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/656F31B644588474D1C46903A7F84373/100, createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Wed Jan 19 07:48:41 CST 2022, time=2022-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268538, encodeId=c15612685387e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat May 22 11:48:41 CST 2021, time=2021-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031388, encodeId=3223103138874, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Thu May 20 23:48:41 CST 2021, time=2021-05-20, status=1, ipAttribution=)]
    2021-05-20 心介

    房颤,临床上碰到很多哦

    0

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