JAMA:抑郁症患者的心血管事件风险增加

2020-12-19 MedSci原创 MedSci原创

通过对22个队列,563255名参与者的随访研究发现,抑郁症状导致患者后续心血管事件风险增加

抑郁症严重困扰患者的生活和工作,给家庭和社会带来沉重的负担,约15%的抑郁症患者死于自杀。近日研究人员考察了抑郁症患者后续的血管疾病(CVDs)风险。
 
本次研究是对个体参与者数据的汇总分析,参与者来自ERFC(162036名参与者,随访至2020年3月)和UK Biobank(401219名参与者,随访至2020年3月)队列,参与者基线无CVD病史,有完整的自我报告抑郁症状的信息,ERFC队列采用CES-D评分评估参与者抑郁症状(0-60分,16分以上为疑似抑郁患者),UK Biobank队列采用PHQ-2(0-6分,3分以上为疑似抑郁患者)评分评估参与者抑郁症状。研究的主要终点为致命或非致命性冠心病(CHD)、中风和CVD。
 
ERFC队列参与者平均年龄63岁,女性占73%,在平均9.5年随访期间,总计发生了5078次CHD事件以及3932次中风事件。主要终点事件风险与CES-D评分log值线性相关,抑郁评分每增加1SD,患者的CHD风险为1.07,中风风险为1.05,CVD风险为1.06CES-D评分最高1/4人群与最低1/4人群相比,每10000随访年中,CHD事件风险为36.3次和29.0次;中风事件分别为28.0次和24.7次;CVD事件分别为62.8次和53.5次。UK Biobank队列参与者平均年龄56岁,女性占55%,在8.1年随访期间,总计记录了4607次CHD事件和3253次中风事件。抑郁评分每增加1SD,患者的CHD风险为1.11,中风风险为1.10,CVD风险为1.10。PHQ-2评分4以及以上患者与0分患者相比,每10000随访年中,CHD事件风险为20.9次和14.2次;中风事件分别为15.3次和10.2次;CVD事件分别为36.2次和24.5次。
 
通过对22个队列,563255名参与者的随访研究发现,抑郁症状导致患者后续心血管事件风险增加。
 
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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, 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    2021-03-14 ms2000000239662574

    抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。

    0

  4. 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createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jun 21 14:17:51 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948160, encodeId=04289481603c, content=抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15b65425966, createdName=ms2000000239662574, createdTime=Sun Mar 14 19:38:38 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910532, encodeId=eb1a910532f5, content=社会应该关注抑郁症, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eec35447202, createdName=ms2000001429810404, createdTime=Thu Dec 24 09:03:09 CST 2020, time=2020-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-24 ms2000001429810404

    社会应该关注抑郁症

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1988604, encodeId=7486198860454, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Sat Jul 10 15:17:51 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643726, encodeId=16a11643e2628, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jun 21 14:17:51 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948160, encodeId=04289481603c, content=抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15b65425966, createdName=ms2000000239662574, createdTime=Sun Mar 14 19:38:38 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910532, encodeId=eb1a910532f5, content=社会应该关注抑郁症, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eec35447202, createdName=ms2000001429810404, createdTime=Thu Dec 24 09:03:09 CST 2020, time=2020-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-22 Jessica

    抑郁症真的好可怜,要关注抑郁症。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1988604, encodeId=7486198860454, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Sat Jul 10 15:17:51 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643726, encodeId=16a11643e2628, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-20 ms3000000630940373

    尤其是围绝经期前后的女性,焦虑抑郁的特别多

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1988604, encodeId=7486198860454, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Sat Jul 10 15:17:51 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643726, encodeId=16a11643e2628, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jun 21 14:17:51 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948160, encodeId=04289481603c, content=抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15b65425966, createdName=ms2000000239662574, createdTime=Sun Mar 14 19:38:38 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910532, encodeId=eb1a910532f5, content=社会应该关注抑郁症, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eec35447202, createdName=ms2000001429810404, createdTime=Thu Dec 24 09:03:09 CST 2020, time=2020-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-19 挖挖机

    难受的时候反正心会痛,伤心这个词是有意义的

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1988604, encodeId=7486198860454, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Sat Jul 10 15:17:51 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643726, encodeId=16a11643e2628, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jun 21 14:17:51 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948160, encodeId=04289481603c, content=抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15b65425966, createdName=ms2000000239662574, createdTime=Sun Mar 14 19:38:38 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910532, encodeId=eb1a910532f5, content=社会应该关注抑郁症, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eec35447202, createdName=ms2000001429810404, createdTime=Thu Dec 24 09:03:09 CST 2020, time=2020-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-19 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1988604, encodeId=7486198860454, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Sat Jul 10 15:17:51 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643726, encodeId=16a11643e2628, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Mon Jun 21 14:17:51 CST 2021, time=2021-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948160, encodeId=04289481603c, content=抑郁情绪导致患者产生行为学方面的改变,增加了心血管疾病的患病风险。, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15b65425966, createdName=ms2000000239662574, createdTime=Sun Mar 14 19:38:38 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910532, encodeId=eb1a910532f5, content=社会应该关注抑郁症, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eec35447202, createdName=ms2000001429810404, createdTime=Thu Dec 24 09:03:09 CST 2020, time=2020-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=910119, encodeId=99ff9101191c, content=抑郁症真的好可怜,要关注抑郁症。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Tue Dec 22 17:18:25 CST 2020, time=2020-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287700, encodeId=ac51128e70053, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Dec 21 01:17:51 CST 2020, time=2020-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909654, encodeId=ab3b9096542e, content=尤其是围绝经期前后的女性,焦虑抑郁的特别多, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=41d25446094, createdName=ms3000000630940373, createdTime=Sun Dec 20 22:05:41 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909371, encodeId=6a8d9093e1d1, content=难受的时候反正心会痛,伤心这个词是有意义的, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0e42452810, createdName=挖挖机, createdTime=Sat Dec 19 14:08:47 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036373, encodeId=434a10363e38b, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sat Dec 19 13:17:51 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909338, encodeId=6e5f909338f3, content=<a href='/topic/show?id=91cf549e3f1' target=_blank style='color:#2F92EE;'>#抑郁症#</a><a href='/topic/show?id=54dc5511bf' target=_blank style='color:#2F92EE;'>#CVD#</a><a href='/topic/show?id=974e51e2810' target=_blank style='color:#2F92EE;'>#心血管#</a>看似无关,实际关联很大。, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54973, encryptionId=91cf549e3f1, topicName=抑郁症), TopicDto(id=5511, encryptionId=54dc5511bf, topicName=CVD), TopicDto(id=51728, encryptionId=974e51e2810, topicName=心血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Dec 19 11:11:34 CST 2020, time=2020-12-19, status=1, ipAttribution=)]
    2020-12-19 hb2008ye

    #抑郁症##CVD##心血管#看似无关,实际关联很大。

    0

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当人出现不开心的情绪时,一般会通过听歌的方式来缓解心情。但最近加拿大一项研究发现,当心情越抑郁,就越容易听悲伤的音乐,从而令情绪无法缓解,陷入更深的痛苦之中。

抑郁症是心理还是生理问题?其实都有!听听专家怎么说!

抑郁症不同于人们通常的理解的情绪波动,在全球3.5亿名抑郁症患者中,每年有近100万人因抑郁症自杀。抑郁症可能潜伏在每个看起来很正常,甚至很“快乐”的普通人身边。

BMJ:爱丁堡产后抑郁量表用于孕产妇抑郁诊断的准确性研究

爱丁堡产后抑郁量表评估11及以上作为孕妇及产后女性抑郁的诊断标准即可达到最大化的敏感性和特异性,标准继续提高对敏感性的提升不显著,但13分以上后特异性大大提升

JAMA Pediatrics:体重担忧和节食在青少年中呈上升趋势,或导致抑郁症

围绕肥胖的公共卫生运动应该考虑到对心理健康的不利影响,并确保避免对体重的歧视。

中国学者发现:肠道微生物紊乱与重度抑郁症有关 Science Advances

重度抑郁症(MDD)是一种常见的精神疾病,表现为患者发生一次或者多次抑郁状态,但是并没有重度躁狂、混合型躁狂以及轻度躁狂史。据数据显示,全球约有3.5亿人饱受抑郁症的折磨,且15%的患者有自杀倾向。