Clin Oral Investig:牙周手术之后,使用盐水漱口可以促进创口愈合

2021-10-11 MedSci原创 MedSci原创

牙周病是最常见的口腔疾病之一,漱口水常用于其治疗或治疗效果的维持。洗必泰是全球研究最多的抗菌剂,在临床上被广泛使用,然而其常见副作用较多。近日,发表于Clin Oral Investig的一项随机研究

牙周病是最常见的口腔疾病之一,漱口水常用于其治疗或治疗效果的维持。洗必泰是全球研究最多的抗菌剂,在临床上被广泛使用,然而其常见副作用较多。近日,发表于Clin Oral Investig的一项随机研究比较了氯酸钠和0.12%洗必泰漱口液对接受牙周微创手术患者的抗炎效果。

研究人员随机选择了47名诊断为牙周炎并有入路翻瓣手术指征的患者。A组:术后使用氯化钠(盐)水基漱口水(试验组)或B组:0.12%洗必泰漱口水(对照组)。在基线(T1)、一周后(T2)和治疗后12周(T3)对全口和手术部位的牙龈指数(GI)进行评估。使用商业试剂盒和平板阅读器测量GCF中的总MMP活性。使用Friedman测试和Wilcoxon签名排名测试比较了T1与T2、T1与T3、T2与T3时间间隔的总MMP活性和GI的中位数,还使用Mann-WhitneyU测试比较了每个时间点的试验和对照。

 

结果显示,测试组的平均GI值在基线与T2(P = 0.0005)和基线与T3(P = 0.003)之间显示出明显的差异。而在每个时间点,试验组和对照组之间没有发现明显的差异(所有-值>0.10)。在术后疼痛值方面,试验组和对照组之间的P值为0.58,表明两组之间同样没有明显差异。

综上所述,该研究结果表明,在微创牙周手术后,使用盐水漱口水显示出与CHX 0.12%相似的抗炎效果。盐水是世界人民都可以使用的漱口水,并可促进牙周手术后的创口愈合过程。

 

原始出处:

 

James Rudolph Collins, et al., Anti-inflammatory effect of salt water and chlorhexidine 0.12% mouthrinse after periodontal surgery: a randomized prospective clinical study. Clin Oral Investig. 2021 Jul;25(7):4349-4357. doi: 10.1007/s00784-020-03748-w. 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2051705, encodeId=0c4f2051e0550, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Jun 02 10:42:28 CST 2022, time=2022-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020681, encodeId=d91520206817b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Jul 01 17:42:28 CST 2022, time=2022-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451368, encodeId=4e0414513688d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Oct 13 04:42:28 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059792, encodeId=031f1059e9217, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Tue Oct 12 14:58:50 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059555, encodeId=10ca1059555df, content=盐水浓度多少啊?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIRJ8uX1iaKrYl6YIzycoNZg7LibvSCM86rFq9L5JM0jkLJoPh7BPKka0JuiagKxNOfHCG9hbibCFpTQA/132, createdBy=1a801742301, createdName=Jenny6666, createdTime=Mon Oct 11 19:32:56 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2051705, encodeId=0c4f2051e0550, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Jun 02 10:42:28 CST 2022, time=2022-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020681, encodeId=d91520206817b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Jul 01 17:42:28 CST 2022, time=2022-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451368, encodeId=4e0414513688d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Oct 13 04:42:28 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059792, encodeId=031f1059e9217, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Tue Oct 12 14:58:50 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059555, encodeId=10ca1059555df, content=盐水浓度多少啊?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIRJ8uX1iaKrYl6YIzycoNZg7LibvSCM86rFq9L5JM0jkLJoPh7BPKka0JuiagKxNOfHCG9hbibCFpTQA/132, createdBy=1a801742301, createdName=Jenny6666, createdTime=Mon Oct 11 19:32:56 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
    2022-07-01 小几洁
  3. [GetPortalCommentsPageByObjectIdResponse(id=2051705, encodeId=0c4f2051e0550, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Jun 02 10:42:28 CST 2022, time=2022-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020681, encodeId=d91520206817b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Jul 01 17:42:28 CST 2022, time=2022-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451368, encodeId=4e0414513688d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Oct 13 04:42:28 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059792, encodeId=031f1059e9217, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Tue Oct 12 14:58:50 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059555, encodeId=10ca1059555df, content=盐水浓度多少啊?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIRJ8uX1iaKrYl6YIzycoNZg7LibvSCM86rFq9L5JM0jkLJoPh7BPKka0JuiagKxNOfHCG9hbibCFpTQA/132, createdBy=1a801742301, createdName=Jenny6666, createdTime=Mon Oct 11 19:32:56 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2051705, encodeId=0c4f2051e0550, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Jun 02 10:42:28 CST 2022, time=2022-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020681, encodeId=d91520206817b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Jul 01 17:42:28 CST 2022, time=2022-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451368, encodeId=4e0414513688d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Oct 13 04:42:28 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059792, encodeId=031f1059e9217, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Tue Oct 12 14:58:50 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059555, encodeId=10ca1059555df, content=盐水浓度多少啊?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIRJ8uX1iaKrYl6YIzycoNZg7LibvSCM86rFq9L5JM0jkLJoPh7BPKka0JuiagKxNOfHCG9hbibCFpTQA/132, createdBy=1a801742301, createdName=Jenny6666, createdTime=Mon Oct 11 19:32:56 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
    2021-10-12 weigq

    👍

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2051705, encodeId=0c4f2051e0550, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Jun 02 10:42:28 CST 2022, time=2022-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020681, encodeId=d91520206817b, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri Jul 01 17:42:28 CST 2022, time=2022-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451368, encodeId=4e0414513688d, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Oct 13 04:42:28 CST 2021, time=2021-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059792, encodeId=031f1059e9217, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Tue Oct 12 14:58:50 CST 2021, time=2021-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1059555, encodeId=10ca1059555df, content=盐水浓度多少啊?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIRJ8uX1iaKrYl6YIzycoNZg7LibvSCM86rFq9L5JM0jkLJoPh7BPKka0JuiagKxNOfHCG9hbibCFpTQA/132, createdBy=1a801742301, createdName=Jenny6666, createdTime=Mon Oct 11 19:32:56 CST 2021, time=2021-10-11, status=1, ipAttribution=)]
    2021-10-11 Jenny6666

    盐水浓度多少啊?

    0

相关资讯

Histol Histopathol:慢性萎缩性胃炎可加重慢性牙周炎,伴有幽门螺杆菌感染和CD4+Th细胞因子浸润

本研究旨在探究慢性萎缩性胃炎对慢性牙周炎的潜在影响,进一步探讨其可能的机制,研究结果已在线发表于Histol Histopathol。

J Periodontol:自我报告的磨牙症与牙周状况的关系

有研究指出了磨牙症与牙周状态之间的关系,但是具体的相关关系仍不清楚。本研究通过在一项大规模的调查中评估自我报告(SR)的磨牙症与牙周状况之间的关系。

Int J Dent Hyg:牙龈肿了,想用漱口水,该选择哪个?

生物膜引起的牙龈炎是最常见的牙周病,如果不在早期进行处理,极有可能发展为牙周炎。既往研究显示,短期使用漱口水(4-7天)可有效治疗牙龈炎。洗必泰(CHX)漱口水因其在抑制牙齿生物膜形成方面的突出疗效而

Gut:好好刷牙,预防癌症!牙周病会增加患癌风险!

如果不想得癌症,除了保持健康的生活习惯外,恐怕要多刷刷牙或多用牙线了!近日,发表在《Gut》上的一项新研究中,报告说:牙龈不健康,患某些类型癌症的风险更高。

J Periodontol:肝病药物熊去氧胆酸可抑制牙周细胞促炎细胞因子的表达

牙周病是一种常见的口腔慢性炎症疾病,包括牙周炎,坏死性牙周炎和作为系统性疾病表现的牙周炎。多种全身性疾病与牙周病的进展和严重程度有关。流行病学证据表明,肝脏受损患者发生牙周病的风险较高。

Odontology:B10细胞会调节宿主免疫从而减少牙槽骨的骨质丧失

牙周炎是由牙周病原体引起的疾病,以牙周炎症和牙槽骨吸收为特征。事实证明,宿主免疫反应促进了牙周炎的发生和发展。本研究旨在建立B10细胞在牙周炎期间调节宿主免疫的功能和机制,研究结果在线发表于Odont