JACC:原发性醛固酮增多症在中国高血压患者中的流行病学研究

2020-04-23 MedSci原创 MedSci原创

在中国,有44.7%的成年人患有高血压,但原发性醛固酮增多症(PA)在中国高血压患者中的发病率尚不清楚。本研究前瞻性地调查了新诊断高血压患者中PA的患病率、特征和预后。

在中国,有44.7%的成年人患有高血压,但原发性醛固酮增多症(PA)在中国高血压患者中的发病率尚不清楚。本研究前瞻性地调查了新诊断高血压患者中PA的患病率、特征和预后。

本研究纳入分析了1020名新诊断的高血压患者,经过长达16个月时间的筛查,有40名诊断为PA,948名为非PA患者,32名为疑似PA患者,PA发病率达4%。与非PA患者相比,PA患者更易出现微量白蛋白尿(p=0.031),但心血管事件的发生率无差异(p=0.927)。手术治疗的患者(n=7)完全生化成功率为100%,完全临床成功率为85.7%。药物治疗的患者(n=29)中,最适控制血压的比例为79%,其中91%(21/23)只需要1种抗高血压药物:盐皮质激素受体拮抗剂。

研究结果显示,原发性醛固酮增多症在中国初诊高血压患者中的发病率为4%以上,初诊高血压患者的PA筛查有良好的临床预后。

原始出处:

Zhixin X et al.Primary Aldosteronism in Patients in China With Recently Detected Hypertension.JACC.2020 Apr.

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    2020-11-22 hbwxf
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    2020-10-29 lovetcm

    #原发性醛固酮增多症#在中国初诊#高血压#患者中的发病率为4%以上,值得关注!

    0

  5. 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    2020-04-25 cmsvly
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    2020-04-23 天地飞扬

    学习了

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