Hypertension: 左心室肥厚能否增加运动量?放心动吧!

2020-03-03 国际循环 国际循环

左心室肥厚是高血压患者预后的重要预测因素。体力活动与较高的左心室质量具有相关性,但同时也降低心血管疾病的风险。近期,Hypertension杂志发表一项研究,旨在探讨两个具体问题,即确定高血压的存在是否改变体力活动与左心室质量的关系以及左心室肥厚能否改变体力活动与预后的有益关系。


左心室肥厚是高血压患者预后的重要预测因素。体力活动与较高的左心室质量具有相关性,但同时也降低心血管疾病的风险。近期,Hypertension杂志发表一项研究,旨在探讨两个具体问题,即确定高血压的存在是否改变体力活动与左心室质量的关系以及左心室肥厚能否改变体力活动与预后的有益关系。
 
研究从普通人群中随机抽取3078例进行超声心动图检查。左心室质量与体表面积有关。受试者的体力活动水平由自我报告,根据活动强度的不同分为不活动、低强度体力活动和中/高强度体力活动3类。测量受试者静息状态下的血压,将其分为正常血压(<140/90 mm Hg)组和高血压(>140/90 mm Hg或抗高血压药物治疗)组。
 
研究结果显示,高血压的存在可显著改变体力活动与左心室质量指数的关系(交互作用试验:P=0.01)。在正常血压组中,体力活动水平越高,左心室质量指数越高(P<0.001),但高血压组患者中无此现象(P=0.90)。体力活动水平与死亡率和心血管结局的改善相关,而与LVH无关[LVH患者:低强度活动HR=0.77(95%CI:0.52~1.15),中度/高强度活动HR=0.61(0.38~0.97);LVH与体力活动水平之间的相互作用试验P=0.71]。
 
这项研究结果提示,血压正常人群增加体力活动水平会导致左心室质量指数较高,而高血压患者中没有这种现象。无论是否存在左心室肥厚,体力活动水平与预后良好相关。
  
参考文献:
Gowsini Joseph, Jacob Louis Marott, et al. Level of Physical Activity, Left Ventricular Mass, Hypertension, and Prognosis. Hypertension. Originally published30 Dec 2019.

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    2020-12-11 xuyu
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    2020-11-18 feather89
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    2020-03-04 1209e435m98(暂无昵称)

    学习了,谢谢分享

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